Abstract
Lichen planus coexisting with diabetes mellitus and hypertension (Grinspan’s syndrome) – description of two cases
- Centre of Periodontal Diseases and Oral Mucosa, Consultation Conservative Dentistry Clinic, Zbigniew Żak Regional Dental Clinic in Krakow, Poland
- Department and Faculty of Periodontology and Clinical Pathologies of Oral Cavity, University Dental Clinic in Kraków, Poland
Introduction
Lichen planus is a chronic skin and oral mucosa disease. Coexistence of the oral form of lichen planus with diabetes and hypertension was described for the first time by Grinspan in 1963.
Case description
Two cases of the occurrence of lichen planus in patients with diagnosed diabetes and hypertension (Grinspan’s syndrome) are presented. In the first case, diabetes and hypertension treatment were accompanied by lesions in the oral cavity and on the skin of shins. In the other case, lichen planus type lesions were manifested only in the oral cavity.
Conclusions
The aetiology of lichen planus remains unclear to some extent. Detailed diagnostics is based on clinical examination, general medical history and histopathological findings. The risk of malignant transformation of oral lichen planus ranges from 0.4 to 5.3% and it regards mainly the erosive form. Regular follow-up visits and oncological vigilance constitute an inseparable part of treatment.
Keywords
oral lichen planus, diabetes, hypertension, Grinspan’s syndrome
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