Neonatal lupus: fighting an unknown enemy?

Marzena Olesińska; Justyna Teliga-Czajkowska

eISSN: 2084-9834
ISSN: 0034-6233

Reumatologia/Rheumatology

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3/2011
vol. 49

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abstract:

Editorial

Neonatal lupus: fighting an unknown enemy?

Marzena Olesińska

,

Justyna Teliga-Czajkowska

Reumatologia 2011; 49, 3: 149–155

Online publish date: 2011/06/06

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Neonatal lupus (NL) affects 2% of children of mothers with detectable levels of anti-SSA/Ro and/or anti-SSB/La. Atrio-ventricular heart block, which constitutes the earliest symptom of the disease, is diagnosed between 18 and 24 weeks of gestation and, together with the developing generalized heart disease, is largely responsible for the prognosis. Recent research studies as well as results of randomized clinical trials significantly increased our knowledge about pathogenesis and clinical course of NL as well as possible therapeutic options.

keywords:

neonatal lupus, congenital heart block, treatment

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Neonatal lupus: fighting an unknown enemy?

Marzena Olesińska , Justyna Teliga-Czajkowska

neonatal lupus, congenital heart block, treatment

Marzena Olesińska

,

Justyna Teliga-Czajkowska