eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
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SCImago Journal & Country Rank
1/2020
vol. 71
 
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abstract:

Quiz. What is your diagnosis?

Martyna Krupińska
1
,
Ewa Kaznowska
2
,
Anna Kruczak
1
,
Katarzyna Mularz
1
,
Jarosław Długosz
3
,
Józef Gancarz
4
,
Janusz Ryś
1

1.
Department of Tumor Pathology, Maria Sklodowska-Curie National Research Institute of Oncology, Cracow Branch, Poland
2.
Department of Pathology Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszow, Poland
3.
Department of Surgical Oncology, Specialist Hospital, Podkarpacki Oncology Center in Brzozow, Poland
4.
Department of Radiology and Imaging Sciences, Specialist Hospital, Podkarpacki Oncology Center in Brzozow, Poland
Pol J Pathol 2020; 71 (1): 75-78
Online publish date: 2020/05/20
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CT scan of the abdominal cavity of a 48-year-old woman revealed extensive thickening of the wall of the pyloric region of the stomach (Fig. 1). During surgery, a gastric tumor was found involving the distal part of the body and the pyloric region of the stomach. The stomach was resected and both macroscopic and histological examination of the surgical specimen showed diffuse neoplastic infiltration covering the full thickness of the stomach wall (Fig. 2) and passing to the surrounding adipose tissue. The tumor texture was built partly of spindle cells forming herring-bone fascicles (Fig. 3), partly of epithelioid cells (Fig. 4, insert) or small round & short spindle cells (Fig. 4). They created hemangiopericytoma-like arrangements (Fig. 5) or formed solid sheets separated by fibrous or myxoid stroma (Fig. 6). Immunohistochemically, tumor cells were characterized by the positive reaction to cytokeratins (AE1/AE3) (Fig. 7), EMA, vimentin (Fig. 8) and Bcl2 antigen (Fig. 9), but did not present reaction against smooth muscle actin, S100 protein, and CD20, HMB45, SOX10, CD31, CD34, CD99 and CD117.


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