Radiofrequency ablation of left-sided accessory pathway with epicardial approach

A 23-year-old sportsman was admitted due to Wolf-Parkinson-White syndrome (WPW) with recurrent wide QRS complex tachycardia. According to Arruda’s algorithm [1], a delta wave pattern in the 12-lead surface electrocardiogram suggested a left-sided accessory pathway (AP) (Figure 1 A). He underwent three unsuccessful radiofrequency (RF) ablations using the transseptal and transaortic approach with early arrhythmia recurrence. Structural heart disease was excluded.
In electrophysiological study presence of left-sided AP with bidirectional conduction was confirmed. With programmed stimulation from the right atrium and apex of the right ventricle, orthodromic atrioventricular reentrant tachycardia was repetitively induced. Using the electroanatomical 3D mapping system Carto 3 UniVu, an irrigated ablation catheter with contact force measurement Thermocool SmartTouch (Biosense Webster, Inc., Diamond Bar, CA, USA) and transseptal access, an activation map of the mitral annulus during sinus rhythm was made and confirmed the earliest ventricle activation in the posterolateral segment. Areas of scarring after previous ablation in the left atrium and ventricle were identified with voltage mapping. Despite increased RF energy in those locations the ablation was unsuccessful. Thus, we performed mitral annulus mapping via the coronary sinus (CS) and great cardiac vein and AP potential was identified with local time advance in relation to QRS onset of 22 ms. With single RF ablation pulse durable elimination of AP was achieved (Figure 1 B). In 6-month follow-up, there was no evidence of WPW syndrome recurrence.
Accessory pathways are mostly located in lateral segments of the mitral annulus [1]. When invasive treatment is indicated, RF ablation is the preferable method due to its high effectiveness [2]. Anatomical features of the AP such as a wide muscle band and an oblique or over the coronary sinus course with epicardial location (1.8% of APs) can be challenging [2]. Mapping of the CS via epicardial access should be performed especially when previous endocardial ablation has failed. In the present case, the CS had not been mapped during previous procedures. Ablation in this region may successfully eliminate the AP but often requires more attempts (66.7 vs. 91.7%; single and multiple ablations respectively) [2–4]. However, this approach could increase the risk of complications such as mechanical injury of the CS, which can lead to tamponade and...


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