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eISSN: 2084-9834
ISSN: 0034-6233
Reumatologia/Rheumatology
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6/2011
vol. 49
 
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abstract:
Review paper

Rheumatoid arthritis and urinary tract infections

Ewa Pater
,
Maria Maciejowska-Roge
,
Maria Majdan

Reumatologia 2011; 49, 6: 426–431
Online publish date: 2011/12/28
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The risk of development of urinary tract infections (UTI) in patients (pts) with rheumatoid arthritis (RA) is higher as compared with controls. In the article, based on the recent references, the relationship between RA and UTI is analyzed (Table I). The main causes of the increased rate of UTI in RA pts are: immunological disturbances and treatment with non-biologic and biologic agents. UTI in RA pts significantly increase the risk of death. The new hypothesis about the upper urinary tract infection by Proteus mirabilis as a cause of RA is also discussed. Early diagnosis of UTI in RA pts and anti-urinary tract infection specific management are extremely important for the long-term prognosis in RA.
keywords:

urinary tract infections, rheumatoid arthritis, pathogenesis, disease-modifying antirheumatic drugs







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