eISSN: 2449-8238
ISSN: 2392-1099
Clinical and Experimental Hepatology
Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
SCImago Journal & Country Rank
2/2020
vol. 6
 
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abstract:
Original paper

Searching for the optimal population for hepatitis C virus screening in Poland

Anna Piekarska
1
,
Krzysztof Tomasiewicz
2
,
Waldemar Halota
3
,
Jerzy Jaroszewicz
4
,
Rafał Krygier
5
,
Piotr Małkowski
6
,
Małgorzata Pawłowska
3
,
Krzysztof Simon
7
,
Olga Tronina
8
,
Dorota Zarębska-Michaluk
9
,
Robert Flisiak
10

1.
Department of Infectious Diseases and Hepatology, Medical University of Łódz, Łódź, Poland
2.
Department of Infectious Diseases and Hepatology, Medical University of Lublin, Lublin, Poland
3.
Department of Infectious Diseases and Hepatology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Poland
4.
Department of Infectious Diseases, Medical University of Silesia, Katowice, Poland
5.
State University of Applied Sciences in Konin, Konin, Poland
6.
Department of Surgical and Transplantation Nursing and Extracorporeal Therapies, Medical University of Warsaw, Warsaw, Poland
7.
Department of Infectious Diseases and Hepatology, Wrocław Medical University, Wrocław, Poland
8.
Department of Transplantation Medicine, Nephrology, and Internal Diseases, Medical University of Warsaw, Warsaw, Poland
9.
Department of Infectious Diseases, Jan Kochanowski University, Kielce, Poland
10.
Department of Infectious Diseases and Hepatology, Medical University of Białystok, Białystok, Poland
Clin Exp HEPATOL 2020; 6, 2: 74–76
Online publish date: 2020/04/30
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Aim of the study
The purpose of the study was to select the optimal target population for a possible national hepatitis C virus (HCV) screening program in Poland, based on the most recent available data.

Material and methods
The analysis included 723,654 participants from different populations screened for anti-HCV. Testing was performed in the whole blood using rapid anti-HCV kits. Presence of HCV RNA was additionally demonstrated in some anti-HCV positive patients with the real-time polymerase chain reaction method.

Results
Altogether 3,548 anti-HCV positive individuals were identified, so the prevalence rate in the whole studied population was 0.5%. The highest percentage (1.2%) was shown by diagnostic laboratories, which offered rapid testing for patients visiting their offices during the HCV awareness campaign. Relatively high anti-HCV prevalence of 0.6-0.7% was noted in hospitals and in private medical centers, as well as during music concerts. Surprisingly, the lowest prevalence (0.2%) was observed in general practitioners’ offices. Among 502 anti-HCV positive individuals tested additionally for HCV RNA, viremic presence was demonstrated in 40%.

Conclusions
Anti-HCV testing in Poland should be carried out using rapid anti-HCV kits at the patients’ admission to the hospitals and should also be offered to patients during their visits for any purpose in diagnostic laboratories or private medical centers.

keywords:

HCV, screening, hepatitis

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