eISSN: 2449-8238
ISSN: 2392-1099
Clinical and Experimental Hepatology
Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
vol. 9
Original paper

Shear-wave elastography for evaluation of hepatic stiffness in chronic viral hepatitis B and C

Diana Martonik
Alicja Wandałowicz
Łukasz Supronowicz
1, 2
Anatol Panasiuk
1, 3
Anna Parfieniuk-Kowerda
1, 2
Robert Flisiak
1, 2

Medical University of Bialystok, Bialystok, Poland
Medical University of Bialystok Clinical Hospital, Bialystok, Poland
Voivodeship Hospital in Białystok, Poland
Clin Exp HEPATOL 2023; 9, 2: 179-186
Online publish date: 2023/06/30
View full text Get citation
PlumX metrics:
Aim of the study:
To analyse the consistency between 2D shear-wave elastography (2D-SWE) stiffness and fibrosis in liver biopsy in patients with chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. The secondary aim of the study was to analyse the consistency between liver stiffness in 2D-SWE and transient elastography (TE) measurements in patients with chronic hepatitis B and C.

Material and methods:
The study compared the results of hepatic stiffness assessment with 2D-SWE to available past liver biopsy reports in 153 patients with chronic HBV (n = 51) and HCV (n = 102) infection. In 43 patients with both hepatitides HBV (n = 8) and HCV (n = 35) we performed FibroScan on the same day as 2D-SWE. The appropriate statistical tests were applied for the analysis.

Stiffness values analysed in the whole studied population showed a significant positive correlation with a stage of liver fibrosis in biopsy (r = 0.555, p < 0.001). If 2D-SWE was carried out within 24 months since liver biopsy the consistency of the results was 96%, and if the period between procedures exceeded 24 months the consistency was 81%. In 43 patients with both 2D-SWE and TE the coherence (r = 0.872, p < 0.001) and consistency (95%) between these two methods were high.

Liver stiffness measured with 2D-SWE showed good consistency with stage of liver fibrosis in liver biopsies, particularly in HCV infected patients, and if the period between procedures did not exceed 24 months.


chronic hepatitis C, liver fibrosis, shear wave elastography, liver stiffness, chronic hepatitis B

Quick links
© 2023 Termedia Sp. z o.o.
Developed by Bentus.