ARCHIVAL" /> The influence of oral hormonal supplement therapy on serum gonadotrophins, estrogens, prolactin and growth hormone levels in postmenopausal women with osteopenia
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ISSN: 1231-6407
Ginekologia Praktyczna - - - ARCHIVAL
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1/2006
vol. 14
 
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The influence of oral hormonal supplement therapy on serum gonadotrophins, estrogens, prolactin and growth hormone levels in postmenopausal women with osteopenia

Ewa Żochowska
,
Stanisław Stanosz
,
Krzysztof Sieja
,
Krzysztof Safranow

Gin Prakt 2006; 88, 1: 20-27
Online publish date: 2006/03/17
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The study group comprised 65 women (52,4±3,6) in the early postmenopausal period with osteopenia, divided into three groups depending on the type and route of administration of the products: I – on transdermal placebo, II – on transdermal hormone replacement therapy, III – on oral hormone adjunctive therapy. We observed serum prolactin and growth hormone levels during 12-mounth therapy had no changed since the study was started in women administrated transdermal HRT. Serum estrogen, estron, PRL and GH concentrations significantly high increased already in 3 mounth treatment during oral hormonal adjunctive therapy. IGF-1 level was decreased in group II (oral rout). In group on transdermal therapy the increase BMD L2–L4 was not significantly higher then in women on oral estrogens.
keywords:

hormone replacement therapy, hormone supplement therapy, osteopenia, hormones

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