The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study

Victoria Psomiadou; Anastasia Prodromidou; Elpis Galati; Ioannis D. Kostakis; Athanasios Maliaros; Ioannis Mamais; Nikolaos Blontzos; Fotios Lefkopoulos; Christos Iavazzo; George Vorgias

doi:10.5114/wo.2021.105072

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

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1/2021
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abstract:

Original paper

The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study

Victoria Psomiadou

¹

,

Anastasia Prodromidou

²

,

Elpis Galati

¹

,

Ioannis D. Kostakis

³

,

Athanasios Maliaros

¹

,

Ioannis Mamais

¹

,

Nikolaos Blontzos

¹

,

Fotios Lefkopoulos

¹

,

Christos Iavazzo

¹

,

George Vorgias

¹

Department of Gynaecological Oncology, Metaxa Memorial Cancer Hospital, Piraeus, Greece

Department of Surgical Oncology, Metaxa Memorial Cancer Hospital, Piraeus, Greece

Department of Transplantation, Guy’s Hospital, Guy’s and St Thomas’ NHS Foundation Trust, London, UK

Contemp Oncol (Pozn) 2021; 25 (1): 7–11

DOI: https://doi.org/10.5114/wo.2021.105072

Online publish date: 2021/04/15

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AMA

Psomiadou V, Prodromidou A, Galati E, et al. The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study. Contemporary Oncology/Współczesna Onkologia. 2021;25(1):7-11. doi:10.5114/wo.2021.105072.

APA

Psomiadou, V., Prodromidou, A., Galati, E., D. Kostakis, I., Maliaros, A.,  & Mamais, I. et al. (2021). The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study. Contemporary Oncology/Współczesna Onkologia, 25(1), 7-11. https://doi.org/10.5114/wo.2021.105072

Chicago

Psomiadou, Victoria, Anastasia Prodromidou, Elpis Galati, Ioannis D. Kostakis, Athanasios Maliaros, Ioannis Mamais,  and Nikolaos Blontzos et al. 2021. "The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study". Contemporary Oncology/Współczesna Onkologia 25 (1): 7-11. doi:10.5114/wo.2021.105072.

Harvard

Psomiadou, V., Prodromidou, A., Galati, E., D. Kostakis, I., Maliaros, A., Mamais, I., Blontzos, N., Lefkopoulos, F., Iavazzo, C.,  and Vorgias, G. (2021). The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study. Contemporary Oncology/Współczesna Onkologia, 25(1), pp.7-11. https://doi.org/10.5114/wo.2021.105072

MLA

Psomiadou, Victoria et al. "The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study." Contemporary Oncology/Współczesna Onkologia, vol. 25, no. 1, 2021, pp. 7-11. doi:10.5114/wo.2021.105072.

Vancouver

Psomiadou V, Prodromidou A, Galati E, D. Kostakis I, Maliaros A, Mamais I et al. The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study. Contemporary Oncology/Współczesna Onkologia. 2021;25(1):7-11. doi:10.5114/wo.2021.105072.

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Introduction
Our aim was to analyse the feasibility of white blood cell and platelet counts along with their ratios as a prognostic factor in patients who underwent surgery for ovarian mass.

Material and methods
We retrospectively studied the patients admitted in the Department of Gynaecology due to adnexal mass. The potential association of the neutrophil-to-lymphocyte-ratio (NLR), neutrophil-to-monocyte (NMR), platelet-to-lymphocyte (PLR), lymphocyte-to-monocyte (LMR), monocyte-to-platelet, and malignancy was evaluated.

Results
Patients with malignant tumours were found with significantly higher ratios of NLR (p < 0.001) and PLR (p < 0.001) and lower LMR ratio (p < 0.001) compared to those with benign tumours. Furthermore, higher lymphocyte count (p = 0.04) and platelet count (p = 0.004) were found in cancer patients when compared with borderline tumours. No significant variations were detected regarding white blood cell count (p = 0.238), NMR ratio (p = 0.28), platelet-to-neutrophil ratio (p = 0.12), and platelet-to-monocyte ratio (p = 0.34).

Conclusions
Inflammation biomarker ratios can easily and inexpensive assist in distinguishing malignant ovarian tumours from benign ones.

keywords:

The role of inflammation biomarkers in differential diagnosis of pelvic tumours of ovarian origin: a single-centre observational study

Victoria Psomiadou 1 , Anastasia Prodromidou 2 , Elpis Galati 1 , Ioannis D. Kostakis 3 , Athanasios Maliaros 1 , Ioannis Mamais 1 , Nikolaos Blontzos 1 , Fotios Lefkopoulos 1 , Christos Iavazzo 1 , George Vorgias 1

pelvic tumours, inflammation biomarkers, differential diagnosis

Victoria Psomiadou

¹

,

Anastasia Prodromidou

²

,

Elpis Galati

¹

,

Ioannis D. Kostakis

³

,

Athanasios Maliaros

¹

,

Ioannis Mamais

¹

,

Nikolaos Blontzos

¹

,

Fotios Lefkopoulos

¹

,

Christos Iavazzo

¹

,

George Vorgias

¹