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Folia Neuropathologica
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2/2022
vol. 60
 
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abstract:
Review paper

WHO CNS5 2021 classification of gliomas: a practical review and road signs for diagnosing pathologists and proper patho-clinical and neuro-oncological cooperation

Aleksandra Sejda
1
,
Wiesława Grajkowska
2
,
Joanna Trubicka
2
,
Ewa Szutowicz
3
,
Tomasz Kazimierz Wojdacz
4
,
Wojciech Kloc
5, 6
,
Ewa Iżycka-Świeszewska
7, 8

1.
Department of Pathomorphology and Forensic Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland
2.
Department of Pathology, The Children’s Memorial Health Institute, Warsaw, Poland
3.
Department of Oncology and Radiotherapy, Medical University of Gdansk, Gdansk, Poland
4.
Independent Clinical Epigenetics Laboratory, Pomeranian Medical University in Szczecin, Poland
5.
Department of Neurosurgery, Copernicus Hospital in Gdansk, Poland
6.
Department of Psychology, Health Sociology and Public Health School, University of Warmia and Mazury, Olsztyn
7.
Department of Pathology and Neuropathology, Medical University of Gdansk, Gdansk, Poland
8.
Department of Pathomorphology, Copernicus Hospital in Gdansk, Poland
Folia Neuropathol 2022; 60 (2): 137-152
DOI: https://doi.org/10.5114/fn.2022.118183
Online publish date: 2022/06/30
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The 5th edition of World Health Organization (WHO) Central Nervous System (CNS) tumours classification has transformed the pathological diagnosis of gliomas from purely histological to the multilayered integrated one with molecular biomarkers necessary for proper classification, risk stratification, and prognostic-predictive clinical purposes. Because of deep and important changes in taxonomy and diagnostic approach to gliomas, this manuscript is a review of WHO CNS classification 5th edition with general testing guidance for pathologists and clinicians working in neuro-oncology.
keywords:

gliomas, classification, WHO, 5th edition, neuropathology
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