Menopause Review
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eISSN: 2299-0038
ISSN: 1643-8876
Menopause Review/Przegląd Menopauzalny
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2/2011
vol. 10
 
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abstract:
Review paper

Premature ovarian failure

Joanna Tkaczuk-Włach
,
Małgorzata Sobstyl
,
Grzegorz Jakiel

Przegląd Menopauzalny 2011; 2: 163–168
Online publish date: 2011/04/28
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Premature ovarian failure (POF) is a syndrome characterized by amenorrhoea, high levels of gonadotropins (FSH and LH) and hypoestrogenism before the age of 40. It is a disorder affecting approximately 1% of women. The known causes include: genetic – X chromosome abnormalities and autosomal genetic conditions, autoimmune conditions, and iatrogenic and environmental factors. Management involves hormone replacement therapy and infertility treatment.
keywords:

ovary, amenorrhea, hypoestrogenism, infertility, premature ovarian failure (POF)


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