A malignant astrocytoma with uncommon angiocentric features and dot-like EMA expression

Wojciech Kuncman; Marcin Braun; Łukasz Kuncman; Piotr Kupnicki; Michał Piotrowski; Dorota Jesionek-Kupnicka; Radzisław Kordek

doi:10.5114/wo.2018.78944

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

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3/2018
vol. 22

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abstract:

Case report

A malignant astrocytoma with uncommon angiocentric features and dot-like EMA expression

Wojciech Kuncman

,

Marcin Braun

,

Łukasz Kuncman

,

Piotr Kupnicki

,

Michał Piotrowski

,

Dorota Jesionek-Kupnicka

,

Radzisław Kordek

Contemp Oncol (Pozn) 2018; 22 (3): 205-208

DOI: https://doi.org/10.5114/wo.2018.78944

Online publish date: 2018/09/30

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Angiocentric features are uncommon in high-grade World Health Organisation (WHO) brain tumours, whilst they are typical for WHO grade I tumours, e.g. angiocentric gliomas. We present an unusual glial tumour that occurred in a 59-year-old man. The tumour had equivocal radiologic and histopathologic features, especially a characteristic angiocentric pattern, low-to-moderate Ki67, and dot-like epithelial membrane antigen expression. The tumour did not show features characteristic for glioblastoma; however, it recurred as glioblastoma four months later. Based on this case, we show that high-grade WHO brain tumours may show an angiocentric pattern typical for low-grade WHO brain tumours, such as angiocentric gliomas.

keywords:

A malignant astrocytoma with uncommon angiocentric features and dot-like EMA expression

Wojciech Kuncman , Marcin Braun , Łukasz Kuncman , Piotr Kupnicki , Michał Piotrowski , Dorota Jesionek-Kupnicka , Radzisław Kordek

angiocentric glioma, glioblastoma, anaplastic astrocytoma, ependymal differentiation, angiocentric features

Wojciech Kuncman

,

Marcin Braun

,

Łukasz Kuncman

,

Piotr Kupnicki

,

Michał Piotrowski

,

Dorota Jesionek-Kupnicka

,

Radzisław Kordek