eISSN: 1897-4317
ISSN: 1895-5770
Gastroenterology Review/Przegląd Gastroenterologiczny
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SCImago Journal & Country Rank
3/2015
vol. 10
 
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abstract:
Systematic review/Meta-analysis

A meta-analysis of ursodeoxycholic acid therapy versus combination therapy with corticosteroids for PBC-AIH-overlap syndrome: evidence from 97 monotherapy and 117 combinations

Huawei Zhang
,
Sainan Li
,
Jing Yang
,
Yuanyuan Zheng
,
Jianrong Wang
,
Wenxia Lu
,
Yuqing Zhou
,
Qin Yin
,
Rong Zhu
,
Chuanyong Guo

Prz Gastroenterol 2015; 10 (3): 148–155
Online publish date: 2015/04/28
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In this study, a meta-analysis of randomised controlled trials that compared ursodeoxycholic acid (UDCA) monotherapy with therapies combining UDCA and corticosteroids was performed. We found that combination therapy with UDCA and corticosteroids was more effective than UDCA monotherapy for primary biliary cirrhosis-autoimmune hepatitis-overlap syndrome.
keywords:

meta-analysis, ursodeoxycholic acid, corticosteroids, combination therapy, overlap syndrome

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