Advances in Interventional Cardiology
eISSN: 1897-4295
ISSN: 1734-9338
Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej
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SCImago Journal & Country Rank
3/2025
vol. 21
 
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abstract:
Original paper

Analysis of secondary cardiac prevention in patients after myocardial infarction enrolled in the Coordinated Care Program in Patients after Myocardial Infarction (KOS-MI): a single-center experience

Marta Mazur
1
,
Aleksandra Kolarczyk-Haczyk
1
,
Patrycja Sochań
1
,
Maksymilian Grajek
1
,
Mariusz Gąsior
2
,
Maciej Rogala
3
,
Paweł Kaźmierczak
1
,
Piotr Jankowski
4
,
Krzysztof Milewski
1
,
Paweł E. Buszman
5
,
Piotr Buszman
1

  1. American Heart of Poland, Katowice, Poland
  2. 3rd Department of Cardiology, Medical University of Silesia, Silesian Center for Heart Diseases, Zabrze, Poland
  3. Faculty of Health Science, Institute of Public Health, Jagiellonian University Medical College, Krakow, Poland
  4. Department of Internal Medicine and Geriatric Cardiology, Centre of Postgraduate Medical Education, Warsaw, Poland
  5. Jan Długosz University, Czestochowa, Poland
Adv Interv Cardiol 2025; 21, 3 (81): 358–365
Online publish date: 2025/09/15
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Introduction:
The Coordinated Care Program in Patients after Myocardial Infarction (KOS-MI) has substantially reduced mortality and heart failure-related hospitalizations through its comprehensive approach, including unlimited rehabilitation, cardiologist ambulatory care, complete revascularization, and electrotherapy in various long-term studies.

Aim:
This study evaluated the outcomes and adherence to secondary preventive measures in patients who completed the KOS-MI Program 1 year and 3 years after myocardial infarction.

Material and methods:
We conducted a retrospective registry involving 331 myocardial infarction patients who participated in the KOS-MI Program. Baseline and follow-up data included laboratory results (low density-lipoprotein (LDL) and glucose levels), echocardiography assessments, and drug compliance records.

Results:
At 12 months, 79.2% of patients (n = 262) had completed the program. Among them, 69.1% were men, and 46.2% presented with ST-elevation myocardial infarction. Complete revascularization was achieved in 55.7% of cases. Patients engaged in stationary or ambulatory rehabilitation constituted 56.1% and 43.9%, respectively. Notably, LDL levels significantly decreased from 129 mg/dl to 85.8 mg/dl (p < 0.001), with 19.1% of cases achieving the LDL goal of < 55 mg/dl. An HbA1c level below 7% was achieved by only 49% of diabetes patients. Left ventricular ejection fraction (LVEF) showed a statistically significant improvement (48.3% vs. 56.1%; p = 0.001). Drug adherence to dual antiplatelet therapy was 100%, while statin adherence was 99.6%.

Conclusions:
The KOS-MI Program has significantly reduced LDL cholesterol levels and improved LVEF, especially in patients with the lowest initial LVEF. Future research should focus on optimizing LDL management and exploring long-term outcomes related to left ventricular function.

keywords:

cardiac rehabilitation, myocardial infarction, preventive cardiology, secondary prevention

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