Przegląd Dermatologiczny

Pełna treść

3/2026 vol. 113
Artykuł oryginalny

Comparative Analysis of the Quality-of-Life Improvement Between Isotretinoin and Benzoyl Peroxide in Adolescents with Acne

Rena Raad Helmi 1
,
Samar A. Jasim 2
,
Wassan Nori 3

  1. Department of Dermatology Faculty of Medicine, Mustansiriyah University, Baghdad, Iraq

  2. Department of Dermatology, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

  3. Department of Obstetrics and Gynecology, Faculty of Medicine, Mustansiriyah University, Baghdad, Iraq

Dermatol Rev/Przegl Dermatol 2026, 113, 135–142

DOI: https://doi.org/10.5114/dr.2026.164193
Data publikacji online: 2026/09/09
Plik artykułu
Comparative Analysis.pdf
Confronting perimenopausal women’s knowledge of coronary heart disease with their health behaviours. Controversial role of hormone replacement therapy in the protection of coronary heart disease
  1. Lynn D.D., Umari T., Dunnick C.A., Dellavalle R.P.L.: The epidemiology of acne vulgaris in late adolescence. Adolesc Health Med Ther 2016, 7, 13-25.
  2. Heng A.H.S., Chew F.T.: Systematic review of the epidemiology of acne vulgaris. Sci Rep 2020, 10, 5754.
  3. Olsen J.R., Gallacher J., Finlay A.Y., Piguet V., Francis N.A.: Quality of life impact of childhood skin conditions measured using the Children’s Dermatology Life Quality Index (CDLQI): a meta-analysis. Br J Dermatol 2016, 174, 853-861.
  4. Hossaini F.S., Soltaninejad H., Ahmadpour F., Akhcheloo M., Sharifi N.: Acne prevalence and related factors in female students: a cross-sectional study. J Health Res Develop 2025, 3, 59-68.
  5. Dhawan S., Nardo C.J.: The impact on acne treatment regimens if benzoyl peroxide-containing products are removed from the market. J Drugs Dermatol 2025, 24, 586-589.
  6. Bagatin E., Costa C.S., Rocha M.A., Picosse F.R., Kamamoto C.S.L., Pirmez R., et al.: Consensus on the use of oral isotretinoin in dermatology – Brazilian Society of Dermatology. An Bras Dermatol 2020, 95 Suppl 1, 19-38.
  7. Bhushan H., Grewal L., Narang R., Singh T., Mishra M., Sood A.: Effect of isotretinoin on quality of life in patients with acne vulgaris: a follow-up study from a tertiary care center. Int J Acad Med Pharm 2024, 6, 145-149.
  8. Khaleel F.F.: Risk factors of acne vulgaris among Mosul University students from Iraq. Iraqi J Med Sci 2022, 20, 51-58.
  9. Sadiq M.A., Salih A.A., Jamil N.F.: Acne among medical students in Baghdad, pattern and associated factors. Int J Family Med Healthcare 2023, 2, 1-7.
  10. Ahmed A.A.A., Nayaf M.S., Ahmed H.S.: Psychosocial impact of acne vulgaris among adolescent Iraqi patients. Syst Rev Pharm 2020, 11, 800-803.
  11. Liu Y.T., Wang Y.W., Tu C., Ren J.W., Huo J., Nan X.J., et al.: Recommendations for managing adult acne and adolescent acne based on an epidemiological study conducted in China. Sci Rep 2024, 14, 16327.
  12. Adityan B., Kumari R., Thappa D.M.: Scoring systems in acne vulgaris. Indian J Dermatol Venereol Leprol 2009, 75, 323-326.
  13. Hacivelioglu S., Gungor A.N.C., Gencer M., Uysal A., Hizli D., Koc E., et al.: Acne severity and the Global Acne Grading System in polycystic ovary syndrome. Int J Gynaecol Obstet 2013, 123, 33-36.
  14. Al-Kathiri L., Al-Najjar T.: Severe nodulocystic acne not responding to isotretinoin therapy successfully treated with oral dapsone. Oman Med J 2018, 33, 433-436.
  15. Yang Z., Zhang Y., Lazic Mosler E., Hu J., Li H., Zhang Y., et al.: Topical benzoyl peroxide for acne. Cochrane Database Syst Rev 2020, 3, CD011154.
  16. Lewis-Jones M.S., Finlay A.Y.: The Children’s Dermatology Life Quality Index (CDLQI): initial validation and practical use. Br J Dermatol 1995, 132, 942-949.
  17. Jones-Caballero M., Chren M.M., Soler B., Pedrosa E., Penas P.F.: Quality of life in mild to moderate acne: relationship to clinical severity and factors influencing change with treatment. J Eur Acad Dermatol Venereol 2007, 21, 219-226.
  18. Huang C.Y., Chang I.J., Bolick N., Hsu W.T., Su C.H., Hsieh T.S., et al.: Comparative efficacy of pharmacological treatments for acne vulgaris: a network meta-analysis of 221 randomized controlled trials. Ann Fam Med 2023, 21, 358-369.
  19. Amarante M.P.C., Paraíso A.O., Costa A.C.A., et al.: Isotretinoína oral <i>versus</i> antibióticos orais no tratamento da acne vulgaris: revisão de evidęncias. Contrib Cięnc Soc 2025, 18, e14924.
  20. Lucena H.A., Gonçalves C.W.L., Santos Neto F.T., de Souza J.A., Ferreira R.D.D., de Oliveira Freitas Filho T.F., et al.: Eficácia do tratamento da acne vulgar: um estudo comparativo entre a isotretinoína e antibióticos. Peer Rev 2023, 5, 94-107.
  21. Secrest A.M., Hopkins Z.H., Frost Z.E., Taliercio V.L., Edwards L.V.D., Biber J.E., et al.: Quality of life assessed using Skindex-16 scores among patients with acne receiving isotretinoin treatment. JAMA Dermatol 2020, 156, 1098-1106.
  22. Chernyshov P.V., Tomas-Aragones L., Manolache L., Svensson A., Marron S.E., Evers A.W.M., et al.: Which acne treatment has the best influence on health-related quality of life? Literature review by the European Academy of Dermatology and Venereology Task Force on Quality of Life and Patient Oriented Outcomes. J Eur Acad Dermatol Venereol 2018, 32, 1410-1419.
  23. Kaikati J., Zoghaib S., Kechichian E., Stephan F., Helou J., Sleilaty G., et al.: The impact of acne treatment on quality of life and self-esteem: a prospective cohort study from Lebanon. Int J Womens Dermatol 2021, 7, 415-421.
  24. Hughes B.R., Norris J.F., Cunliffe W.J.: A double-blind evaluation of topical isotretinoin 0.05%, benzoyl peroxide gel 5% and <i><i>placebo</i></i> in patients with acne. Clin Exp Dermatol 1992, 17, 165-168.
  25. Jacobs A., Starke G., Rosumeck S., Nast A.: Systematic review on the rapidity of the onset of action of topical treatments in the therapy of mild-to-moderate acne vulgaris. Br J Dermatol 2014, 170, 557-564.
  26. Layton A.M., Bettoli V., Delore V., Puentes E., Tan J.K.L.: The burden of acne vulgaris on health-related quality of life and psychosocial well-being domains: a systematic review. Am J Clin Dermatol 2026, 27, 17-47.
  27. Pethani N., Pethani Y.: Psychological impact of acne on adolescents in Ahmedabad: a cross-sectional study on social interactions, self-perception, and lifestyle changes. South East Eur J Public Health 2025, 24, 1767-1776.
  28. Vallerand I.A., Lewinson R.T., Farris M.S., Sibley C.D., Ramien M.L., Bulloch A.G.M., et al.: Efficacy and adverse events of oral isotretinoin for acne: a systematic review. Br J Dermatol 2018, 178, 76-85.
  29. Fritts H., Frasier K., Johnson A.: Advancements in topical treatments for acne vulgaris: a comprehensive review of efficacy, safety, and patient satisfaction. Clin Dermatol Surg 2024, 2(2). https://doi.org/10.61853/6zczv952.
  30. Tasneem T., Begum A., Chowdhury M.R.K., Rahman S., Macassa G., Manzoor J., et al.: Effects of acne severity and acne-related quality of life on depressive symptoms among adolescents and young adults: a cross-sectional study in Bangladesh. Front Psychol 2023, 14, 1153101.
Copyright: © 2026 Polish Dermatological Association. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
ZGŁASZANIE PRAC
Indeks osobowy
Udostępnij
without publication fees
without publication fees
Dostępne w
Zintergrowane z
plagiat pl
Zasady redakcyjne
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications