Diet as therapeutic intervention in Crohn’s disease

Martyna Więcek; Paulina Panufnik; Karolina Pomorska; Konrad Lewandowski; Grażyna Rydzewska

doi:10.5114/pg.2022.116376

eISSN: 1897-4317
ISSN: 1895-5770

Gastroenterology Review/Przegląd Gastroenterologiczny

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2/2022
vol. 17

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abstract:

Review paper

Diet as therapeutic intervention in Crohn’s disease

Martyna Więcek

¹

,

Paulina Panufnik

¹

,

Karolina Pomorska

¹

,

Konrad Lewandowski

¹

,

Grażyna Rydzewska

¹

Clinical Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Subunit, Central Clinical Hospital of the Ministry of Interior and Administration, Warsaw, Poland

Gastroenterology Rev 2022; 17 (2): 96–102

DOI: https://doi.org/10.5114/pg.2022.116376

Online publish date: 2022/05/19

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Diet plays an important role in the pathogenesis of inflammatory bowel disease. It has an impact on microbiome, host barrier, and immune response. Clinical studies indicate that various dietary interventions such as exclusive enteral nutrition and exclusion diets might be useful for induction of remission in mild to moderate Crohn’s disease, but also for patients failing biological therapy. Current treatment strategies try to solve the problem of poor patient compliance due to the required strict dietary regime. The number of adverse events associated with the use of dietary alternatives is incomparable with the side effects of glucocorticosteroids or biological treatment, which makes them a tempting therapeutic option.

keywords:

Diet as therapeutic intervention in Crohn’s disease

Martyna Więcek 1 , Paulina Panufnik 1 , Karolina Pomorska 1 , Konrad Lewandowski 1 , Grażyna Rydzewska 1

Crohn’s disease exclusion diet, exclusive enteral nutrition, parenteral nutrition, low-FODMAP diet, gluten-free diet, butyric acid

Martyna Więcek

¹

,

Paulina Panufnik

¹

,

Karolina Pomorska

¹

,

Konrad Lewandowski

¹

,

Grażyna Rydzewska

¹