eISSN: 2083-8441
ISSN: 2081-237X
Pediatric Endocrinology Diabetes and Metabolism
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Journal's reviewers Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
SCImago Journal & Country Rank

 
3/2019
vol. 25
 
Share:
Share:
more
 
 
abstract:
Original paper

Difficulties in diagnostics of polycystic ovary syndrome in adolescents – a preliminary study

Monika A. Milczarek
,
Anna M. Kucharska
,
Ada Borowiec

Pediatr Endocrinol Diabetes Metab 2019; 25 (3): 122-126
Online publish date: 2019/09/24
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Introduction
Polycystic ovary syndrome (PCOS) accounts for 72–84% of adult hyperandrogenism, and in the majority of cases it begins during puberty. The diagnosis based on the Rotterdam criteria seem not to be efficient enough in adolescents.

Aim of the study
was the analysis of the frequency of PCOS according to Rotterdam criteria in adolescents.

Material and methods
Twenty-six girls with menstrual disorders and/or symptoms of hyperandrogenism two years after menarche were enrolled. We analysed medical history, clinical symptoms, pelvic ultrasound, and testosterone concentration (T).

Results
The study group was divided into three subgroups: with isolated cutaneous manifestation (CM) of hyperandrogenism (n = 6), with isolated menstrual disorders (MD; n = 10), and with cutaneous manifestation and menstrual disorders (CMMD; n = 10). We compared total T (cut-off points: > 42 ng/dl and > 55 ng/dl) and polycystic ovarian morphology (PCOM) occurrence. PCOM was detected in 54% of girls, with the highest proportion in the MD group (70%). Using a testosterone cut-off point of > 42 ng/dl, hyperandrogenaemia was confirmed in 81% with a preponderance of the CMMD group (90%). Eleven patients (42%) met all Rotterdam criteria. By more restrict-ed criteria with a testosterone cut-off point of > 55 ng/dl, hyperandrogenaemia was confirmed in 54% of patients, with the highest con-tribution in the CMMD group (70%), and seven patients (27%) met all Rotterdam criteria. Study did not show any correlation between T and ovarian volume (p = 0.695; Rs= 0.08).

Conclusions
In our study 27% of patients suspected of PCOS met all Rotterdam criteria. The co-occurrence of symptoms increases the probability of hyperandrogenaemia.

keywords:

hyperandrogenism, menstrual disorders, hirsutism, PCOS, adolescents

Quick links
© 2019 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe