Effects of velocity loss with blood flow restriction in full squat 
on strength gains, neuromuscular adaptations, and muscle 
hypertrophy

Juan Sánchez-Valdepeñas; Luis Rodiles-Guerrero; Pedro Jesús Cornejo-Daza; Jose Antonio Paez-Maldonado; Clara Cano-Castillo; Beatriz Bachero-Mena; Miguel Sánchez-Moreno; Juan José González-Badillo; Eduardo Saez de Villarreal; Fernando Pareja-Blanco

doi:10.5114/biolsport.2025.151657

eISSN: 2083-1862
ISSN: 0860-021X

Biology of Sport

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Original paper

Effects of velocity loss with blood flow restriction in full squat on strength gains, neuromuscular adaptations, and muscle hypertrophy

Juan Sánchez-Valdepeñas

^{1, 2}

,

Luis Rodiles-Guerrero

^{2, 3}

,

Pedro Jesús Cornejo-Daza

^{2, 4, 3}

,

Jose Antonio Paez-Maldonado

^{2, 5}

,

Clara Cano-Castillo

⁴

,

Beatriz Bachero-Mena

^{2, 3}

,

Miguel Sánchez-Moreno

^{2, 6}

,

Juan José González-Badillo

⁴

,

Eduardo Saez de Villarreal

⁴

,

Fernando Pareja-Blanco

^{2, 4}

Physical Education and Sports Department, Cardenal Spínola CEU Andalucía University, Bormujos, Sevilla, Spain
Science-Based Training Research Group, Physical Performance and Sports Research Center, Universidad Pablo de Olavide, Seville, Spain
Department of Human Movement and Sport Performance, University of Seville, Spain
Faculty of Sports Sciences, Department of Sports and Computer Sciences, Universidad Pablo de Olavide, Seville, Spain
University of Osuna (Centre attached to the University of Seville), Osuna, Spain
Department of Physical Education and Sports, University of Seville, Seville, Spain

Biol Sport. 2026; 43: 65–75

DOI: https://doi.org/10.5114/biolsport.2025.151657

Online publish date: 2025/08/05

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AMA

Sánchez-Valdepeñas J, Rodiles-Guerrero L, Cornejo-Daza P, et al. Effects of velocity loss with blood flow restriction in full squat 
on strength gains, neuromuscular adaptations, and muscle 
hypertrophy. Biology of Sport. 2026;43(1):65-75. doi:10.5114/biolsport.2025.151657.

APA

Sánchez-Valdepeñas, J., Rodiles-Guerrero, L., Cornejo-Daza, P., Paez-Maldonado, J., Cano-Castillo, C.,  & Bachero-Mena, B. et al. (2026). Effects of velocity loss with blood flow restriction in full squat 
on strength gains, neuromuscular adaptations, and muscle 
hypertrophy. Biology of Sport, 43(1), 65-75. https://doi.org/10.5114/biolsport.2025.151657

Chicago

Sánchez-Valdepeñas, Juan, Luis Rodiles-Guerrero, Pedro Jesús Cornejo-Daza, Jose Antonio Paez-Maldonado, Clara Cano-Castillo, Beatriz Bachero-Mena,  and Miguel Sánchez-Moreno et al. 2026. "Effects of velocity loss with blood flow restriction in full squat 
on strength gains, neuromuscular adaptations, and muscle 
hypertrophy". Biology of Sport 43 (1): 65-75. doi:10.5114/biolsport.2025.151657.

Harvard

Sánchez-Valdepeñas, J., Rodiles-Guerrero, L., Cornejo-Daza, P., Paez-Maldonado, J., Cano-Castillo, C., Bachero-Mena, B., Sánchez-Moreno, M., González-Badillo, J., de Villarreal, E.,  and Pareja-Blanco, F. (2026). Effects of velocity loss with blood flow restriction in full squat 
on strength gains, neuromuscular adaptations, and muscle 
hypertrophy. Biology of Sport, 43(1), pp.65-75. https://doi.org/10.5114/biolsport.2025.151657

MLA

Sánchez-Valdepeñas, Juan et al. "Effects of velocity loss with blood flow restriction in full squat 
on strength gains, neuromuscular adaptations, and muscle 
hypertrophy." Biology of Sport, vol. 43, no. 1, 2026, pp. 65-75. doi:10.5114/biolsport.2025.151657.

Vancouver

Sánchez-Valdepeñas J, Rodiles-Guerrero L, Cornejo-Daza P, Paez-Maldonado J, Cano-Castillo C, Bachero-Mena B et al. Effects of velocity loss with blood flow restriction in full squat 
on strength gains, neuromuscular adaptations, and muscle 
hypertrophy. Biology of Sport. 2026;43(1):65-75. doi:10.5114/biolsport.2025.151657.

PlumX metrics:

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