Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection

Yuan Li; Xuefeng Xia; Jing Zhang; Zhiqiang Song; Liya Zhou; Yaopeng Zhang; Yonghui Huang; Yanyan Shi; Eamonn M.M. Quigley; Shigang Ding

doi:10.5114/pg.2015.48995

Abstract

2/2015 vol. 10

Review paper

Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection

Yuan Li

,

Xuefeng Xia

,

Jing Zhang

,

Zhiqiang Song

,

Liya Zhou

,

Yaopeng Zhang

,

Yonghui Huang

,

Yanyan Shi

,

Eamonn M.M. Quigley

,

Shigang Ding

Prz Gastroenterol 2015; 10 (2): 78–82

DOI: https://doi.org/10.5114/pg.2015.48995

Online publish date: 2015/02/10

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AMA

Li Y, Xia X, Zhang J, et al. Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection. Gastroenterology Review/Przegląd Gastroenterologiczny. 2015;10(2):78-82. doi:10.5114/pg.2015.48995.

APA

Li, Y., Xia, X., Zhang, J., Song, Z., Zhou, L., & Zhang, Y. et al. (2015). Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection. Gastroenterology Review/Przegląd Gastroenterologiczny, 10(2), 78-82. https://doi.org/10.5114/pg.2015.48995

Chicago

Li, Yuan, Xuefeng Xia, Jing Zhang, Zhiqiang Song, Liya Zhou, Yaopeng Zhang, and Yonghui Huang et al. 2015. "Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection". Gastroenterology Review/Przegląd Gastroenterologiczny 10 (2): 78-82. doi:10.5114/pg.2015.48995.

Harvard

Li, Y., Xia, X., Zhang, J., Song, Z., Zhou, L., Zhang, Y., Huang, Y., Shi, Y., Quigley, E., and Ding, S. (2015). Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection. Gastroenterology Review/Przegląd Gastroenterologiczny, 10(2), pp.78-82. https://doi.org/10.5114/pg.2015.48995

MLA

Li, Yuan et al. "Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection." Gastroenterology Review/Przegląd Gastroenterologiczny, vol. 10, no. 2, 2015, pp. 78-82. doi:10.5114/pg.2015.48995.

Vancouver

Li Y, Xia X, Zhang J, Song Z, Zhou L, Zhang Y et al. Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection. Gastroenterology Review/Przegląd Gastroenterologiczny. 2015;10(2):78-82. doi:10.5114/pg.2015.48995.

Patients with inflammatory bowel disease (IBD) are at risk of developing haemophagocytic lymphohistiocytosis (HLH) because of chronic systemic inflammation as well as exposure to immunosuppressive medications. The two main causes of HLH in IBD patients are infection with cytomegalovirus and Epstein-Barr virus. Patients with Crohn’s disease are more susceptible to HLH than those with ulcerative colitis. The majority of cases are seen in people receiving an immunosuppressive regimen that included thiopurines.