eISSN: 2300 - 8660
ISSN: 0031-3939
Pediatria Polska - Polish Journal of Paediatrics
Bieżący numer Archiwum Artykuły zaakceptowane O czasopiśmie Rada naukowa Bazy indeksacyjne Kontakt Zasady publikacji prac
SCImago Journal & Country Rank

5/2019
vol. 94
 
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Hepatological aspects of Epstein-Barr virus infection in children

Justyna Moppert
1
,
Małgorzata Pawłowska
1, 2

1.
The Tadeusz Browicz Provincial Hospital for Infectious Diseases and Observation, Bydgoszcz, Poland
2.
Department of Infectious Diseases and Hepatology, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland
Data publikacji online: 2019/11/19
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The Epstein-Barr virus (EBV), belonging to the Herpesviridae family, is widespread in the world today. The most typical features of infectious mononucleosis include a triad of symptoms in the form of fever, cervical lymphadenopathy, and pharyngitis. Primary infection in the youngest children is usually asymptomatic and self-limiting. Hepatitis affects a significant proportion of patients and is usually a mild and self-limiting condition. Cholangitis is less common in the paediatric population and requires only symptomatic treatment in most cases. In contrast, in patients with immunodeficiency, EBV infection may be the cause of acute multiple organ failure and death. EBV infection plays an important and multifaceted role in the liver and biliary tract pathology due to its widespread distribution in the paediatric population.