Folia Neuropathologica

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Official journal of the Polish Association of Neuropathologists and M. Mossakowski Medical Research Centre of the Polish Academy of Sciences

Abstracted and indexed in: ISI Master Journal List, ISI Science Citation Index Expanded, Neuroscience Citation Index (NSCI), Index Medicus/MEDLINE, EMBASE, Excerpta Medica, Chemical Abstracts CAS, SciFinder, SciSearch, Scopus, Research Alert, Index Copernicus (IC), KBN, Directory of Open Access Journals (DOAJ), OpenMED, and Polish Medical Library (GBL).

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Zawiadamiamy z ogromnym smutkiem, że 10 października 2025 roku, zmarł po wieloletniej chorobie wybitny specjalista w dziedzinie patomorfologii i neuropatologii prof. dr hab. n. med. Janusz Szymaś.

Wieloletni przewodniczący Stowarzyszenia Neuropatologów Polskich oraz członek Polskiego Towarzystwa Patologów. Były Kierownik Pracowni Patomorfologii Neurochirurgicznej Katedry Anatomii Patologicznej Uniwersytetu Medycznego w Poznaniu. Profesor Janusz Szymaś był autorem wielu prac naukowych oraz pionierem telediagnostyki w Polsce.

It is with great sadness that we announce the passing of Professor Janusz Szymaś, a distinguished specialist in the fields of pathology and neuropathology, on October 10, 2025, after a long illness.

He served for many years as the President of the Association of Polish Neuropathologists and was a member of the Polish Society of Pathologists. He was also the former Head of the Neurosurgical Pathology Laboratory at the Department of Pathological Anatomy of the Poznań University of Medical Sciences.

Professor Janusz Szymaś was the author of numerous scientific publications and a pioneer of telediagnostics in Poland.

Z głębokim żalem zawiadamiamy o nagłej śmierci prof. dr. hab. n. med. Pawła Piotra Liberskiego, wybitnego neurologa i neuropatologa, Członka Stowarzyszenia Neuropatologów Polskich, kierownika Zakładu Patologii Molekularnej i Neuropatologii oraz byłego Prorektora ds. Nauki Uniwersytetu Medycznego w Łodzi. Profesor Paweł Liberski był światowej klasy specjalistą w dziedzinie chorób prionowych, autorem ponad 670 publikacji naukowych, promotorem wielu prac doktorskich i habilitacyjnych, cenionym wykładowcą oraz mentorem. Jego dorobek naukowy i wkład w rozwój medycyny pozostaną trwałym śladem w historii polskiej nauki. Łączymy się w bólu z Rodziną i Bliskimi, składając najszczersze wyrazy współczucia.

It is with deep regret that we inform you of the sudden death of Prof. Paweł Piotr Liberski, MD, PhD, an eminent neurologist and neuropathologist, Member of the Association of Polish Neuropathologists, Head of the Department of Molecular Pathology and Neuropathology and former Vice-Rector for Science at the Medical University of Lodz. Professor Paweł Liberski was a world-class specialist in the field of prion diseases, the author of over 670 scientific publications, the supervisor of many doctoral and postdoctoral theses, a valued lecturer and mentor. His scientific achievements and contribution to the development of medicine will remain a permanent trace in the history of Polish science. We join in the pain with the Family and Loved Ones, expressing our sincerest condolences.

2/2025
vol. 63

Review paper

Nab-paclitaxel: A revolution in the nano-therapeutic approach to IDH-wildtype glioblastoma

Maria Fareed Siddiqui, Amber Hassan, Muzna Tahir, Fahad Okal, Saleh Baeesa, Alaa Alkhotani, Zayd Jasaniah, Ahmad Fallatah, Eyad Faizo, Dahlia Mirdad, Bashayer A. Althaqafi, Maher Kurdi

Folia Neuropathol 2025; 63 (2): 107-119

Online publish date: 2025-07-07

DOI : https://doi.org/10.5114/fn.2025.152517

Abstract Full text (PDF)

Original paper

Alzheimer’s disease-related a-synuclein gene expression in CA3 subfield of hippocampus in post-ischemic brain during 2-year survival

Ryszard Pluta, Anna Bogucka-Kocka, Jacek Bogucki, Janusz Kocki, Stanisław J. Czuczwar

Folia Neuropathol 2025; 63 (2): 120-126

Online publish date: 2025-07-04

DOI : https://doi.org/10.5114/fn.2025.152012

Abstract Full text (PDF)

Original paper

Effect of the TGF-b signaling pathway on spinal cord ependymoma: A study based on bioinformatics analysis and clinical trials

Yan-dong Fan, Man-li Zhu, Mamutijiang Muertizha, Jia-ming Wang, Kun Luo

Folia Neuropathol 2025; 63 (2): 127-137

Online publish date: 2025-07-10

DOI : https://doi.org/10.5114/fn.2025.152514

Abstract Full text (PDF)

Original paper

Neuregulin 2 reversed astrocytosis in the spinal cord in a mouse model of Alzheimer’s disease

Chong Liu, Qing Xie, Jun-Ping Xu, Kai-Ye Hua, Wei-Jiang Zhao

Folia Neuropathol 2025; 63 (2): 138-147

Online publish date: 2025-06-04

DOI : https://doi.org/10.5114/fn.2025.151824

Abstract Full text (PDF)

Original paper

Expression of components involved in cholesterol homeostasis maintenance during experimental autoimmune encephalomyelitis in rat spinal cord

Smilja Todorovic, Katarina Milosevic, Ana Milosevic, Marija M. Janjic, Srdjan J. Sokanovic, Danijela Savic, Irena Lavrnja

Folia Neuropathol 2025; 63 (2): 148-156

Online publish date: 2024-08-02

DOI : https://doi.org/10.5114/fn.2024.141376

Abstract Full text (PDF)

Original paper

Efficacy of Buyang Huanwu Decoction in treating acute ischemic stroke based on the neurovascular unit

Qingyang Dong

Folia Neuropathol 2025; 63 (2): 157-165

Online publish date: 2025-07-03

DOI : https://doi.org/10.5114/fn.2025.151207

Abstract Full text (PDF)

Original paper

Down-regulation of PGAM5 attenuates spinal cord injury-induced neuronal injury by inhibiting ASK-1/p38/NF-kB signaling

Junjie Guan, Xin Xu, Runze Zhang, Yingchu Gu, Xiangdong Chen

Folia Neuropathol 2025; 63 (2): 166-175

Online publish date: 2024-07-10

DOI : https://doi.org/10.5114/fn.2024.141372

Abstract Full text (PDF)

Original paper

The early predictive value of maternal serum PAPP-A concentration at 11-14 weeks of pregnancy for preeclampsia

Qing Wang, Weiping Zhang, Wushan Li, Chunmei Yu

Folia Neuropathol 2025; 63 (2): 176-184

Online publish date: 2024-07-01

DOI : https://doi.org/10.5114/fn.2024.140447

Abstract Full text (PDF)

Original paper

Suppression of the lncRNA TUG1 alleviates neuropathic pain in rats with chronic contractile injury via the miR-29b-3p/HMGB1 axis

Jingjing Dong, Yonghong Ding, Xia Geng, Xiaona Guo, Linkai Jiang, Aiping Ouyang

Folia Neuropathol 2025; 63 (2): 185-197

Online publish date: 2024-08-05

DOI : https://doi.org/10.5114/fn.2024.141512

Abstract Full text (PDF)

Case report

Clinicopathological and neuroradiological presentation in an immuno-deficiency patient with central nervous system recurrence of Burkitt lymphoma: an extremely rare case with complete remission achieved twice after GMALL-B-ALL/NHL2002 and R-MIV protocols

Piotr Glinka, Michał Sobstyl, Grzegorz Rymkiewicz, Karol Karamon, Monika Skowronek-Płachta, Albert Acewicz, Katarzyna Błachnio, Robert Konecki, Marcin Chmielewski

Folia Neuropathol 2025; 63 (2): 198-208

Online publish date: 2025-07-04

DOI : https://doi.org/10.5114/fn.2025.152574

Abstract Full text (PDF)

Case report

Mild malformation of cortical development with oligodendroglial hyperplasia in frontal lobe epilepsy (MOGHE): a report of the first case in Bulgaria

Dimitar Metodiev, Krassimir Minkin, Petia Dimova, Ingmar Blumcke, Roland Coras, Margarita Ruseva, Rumiana Ganeva, Dimitar Parvanov, Marin Penkov, Sevdalin Nachev

Folia Neuropathol 2025; 63 (2): 209-216

Online publish date: 2024-04-12

DOI : https://doi.org/10.5114/fn.2024.138751

Abstract Full text (PDF)