Persistent pleural effusion in an infant with an unusual diagnosis: congenital alveolar rhabdomyosarcoma

Can Yozgat; Osman Yesilbas; Yilmaz Yozgat; Osman Cemil Akdemir; Ismail Yurtsever; Nur Tekin; Damat Baghishov; Nigar Bayramova; Sahande Elagoz; Fatma Betul Cakir

doi:10.5114/wo.2020.97639

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

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2/2020
vol. 24

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abstract:

Case report

Persistent pleural effusion in an infant with an unusual diagnosis: congenital alveolar rhabdomyosarcoma

Can Yilmaz Yozgat

¹

,

Osman Yesilbas

²

,

Yilmaz Yozgat

³

,

Osman Cemil Akdemir

⁴

,

Ismail Yurtsever

⁵

,

Nur Tekin

⁶

,

Damat Baghishov

⁶

,

Nigar Bayramova

⁶

,

Sahande Elagoz

⁷

,

Fatma Betul Cakir

⁸

Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey

Department of Paediatric Critical Care Medicine, Bezmialem Vakif University, Istanbul, Turkey

Department of Paediatric Cardiology, Bezmialem Vakif University, Istanbul, Turkey

Department of Thoracic Surgery, Bezmialem Vakif University, Istanbul, Turkey

Department of Radiology, Bezmialem Vakif University, Istanbul, Turkey

Department of Paediatrics, Bezmialem Vakif University, Istanbul, Turkey

Department of Pathology, Bezmialem Vakif University, Istanbul, Turkey

Department of Paediatric Haematology and Oncology, Bezmialem Vakif University, Istanbul, Turkey

Contemp Oncol (Pozn) 2020; 24 (2): 132-135

DOI: https://doi.org/10.5114/wo.2020.97639

Online publish date: 2020/07/03

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Rhabdomyosarcoma (RMS) is a malignant form of neoplasm that originates from skeletal muscle. RMSs can exist anywhere in the human body but are more commonly detected in the neck region and extremities. The alveolar type is one of the subtypes of RMS that has a poor prognosis. Because the clinical manifestation of a tumour can be a painless mass, symptoms might be non-contributary to the diagnosis. Herein, a four-month-old girl was admitted to the emergency department with complaints of respiratory distress without a runny nose, cough, and fever. Recurrent effusions subsided with subsequent tube thoracostomy. Video-assisted thoracoscopic surgery (VATS) was performed to determine the aetiology of the recurrent effusion. The Tru-Cut biopsy obtained during VATS resulted in the diagnosis of alveolar rhabdomyosarcoma. Pleural effusion decreased, and the tube drainage was stopped rapidly after first vincristine, actinomycin-D, and cyclophosphamide chemotherapy cycle. Persistent and recurrent pleural effusions should alert physicians to rule out unusual diagnoses like that of our case.

keywords:

Persistent pleural effusion in an infant with an unusual diagnosis: congenital alveolar rhabdomyosarcoma

Can Yilmaz Yozgat 1 , Osman Yesilbas 2 , Yilmaz Yozgat 3 , Osman Cemil Akdemir 4 , Ismail Yurtsever 5 , Nur Tekin 6 , Damat Baghishov 6 , Nigar Bayramova 6 , Sahande Elagoz 7 , Fatma Betul Cakir 8

congenital alveolar rhabdomyosarcoma, childhood, pleural effusion

Can Yilmaz Yozgat

¹

,

Osman Yesilbas

²

,

Yilmaz Yozgat

³

,

Osman Cemil Akdemir

⁴

,

Ismail Yurtsever

⁵

,

Nur Tekin

⁶

,

Damat Baghishov

⁶

,

Nigar Bayramova

⁶

,

Sahande Elagoz

⁷

,

Fatma Betul Cakir

⁸