General Practitioner
eISSN: 2450-4459
ISSN: 2450-3517
Lekarz POZ
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4/2025
vol. 11
 
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abstract:

Potential complications of obesity treatment

Kateryna Baran-Dorosh
1
,
Tomasz Witaszek
2
,
Joanna M. Iskra-Trifunović
3
,
Anna Łosiowska
4
,
Karolina Kłoda
5

  1. NZOZ Kraków-Południe, Kraków
  2. Indywidualna praktyka lekarska, Kraków
  3. Centrum Medyczne Agmed, Mierzyn
  4. Polskie Towarzystwo Medycyny Rodzinnej
  5. Sekcja Naukowa, Polskie Towarzystwo Medycyny Rodzinnej
Online publish date: 2025/10/15
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Obesity is a global public health problem associated with chronic excess body fat and numerous complications, such as type 2 diabetes and cardiovascular disease. Obesity treatment requires a comprehensive approach, including lifestyle modification, pharmacotherapy, and bariatric surgery. Among the medications used in recent years, GLP-1 analogues and dual GLP-1/GIP agonists have gained particular attention, demonstrating high efficacy in weight loss. The aim of this paper was to review the current literature and recommendations on the side effects and complications of obesity treatment. Particular attention was paid to gastrointestinal symptoms associated with incretin-based drug therapy, as well as the incidence of gallstones associated with weight loss. A descriptive summary of the main findings from the latest documents and the resulting recommendations was presented.
keywords:

obesity, complications, gallstones, agents acting on the gastrointestinal tract, treatment
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