Abstract
Randomized controlled effect of treadmill walking exercise on liver enzymes, psychological burden, and erectile dysfunction in men with hepatitis C
- Department of Physical Therapy for Cardiovascular/Respiratory Disorders and Geriatrics, Faculty of Physical Therapy, Cairo University, Giza, Egypt
- Teaching Fellow of Physical Therapy, El-Sahel Teaching Hospital, General Organization for Teaching Hospitals and Institutes GOTHI, Cairo, Egypt
- Department of Dermatology, Andrology and Venereology, El-Sahel Teaching Hospital, General Organization for Teaching Hospitals and Institutes GOTHI, Cairo, Egypt
- Department of Internal Medicine and Geriatrics, Faculty of Physical Therapy, Badr University in Cairo, Cairo, Egypt
- Department of Physical Therapy for Internal Medicine and Geriatrics, Faculty of Physical Therapy, October University for Modern Sciences and Arts, 6th October City, Egypt
Introduction:
Exercise is a simple, safe, and affordable solution that can be easily taught to men with chronic illnesses to improve their psychological burden and sexual health.
Aim:
Since the role of exercise in ameliorating the psychological burden associated with erectile dysfunction (ED) in hepatitis C (HC) men was not explored, this research aimed to explore this role.
Material and methods:
This HC study was a randomized-controlled exercise-rehabilitation trial. Recruitment of HC men with ED was conducted from El-Sahel Teaching Hospital, Cairo, Egypt. Men (n = 46) were randomly assigned to a 12-week walking-exercise group (WEG, n = 23 HC men with ED received a one-hour treadmill walking 3 times weekly) or a control group (n = 23 HC men with ED, who did not change their daily physical activity during the research period). Besides Beck’s Depression Inventory (BDI), Arabic Version of the Five-Item Version International Index of Erectile Function (IIEF-5), Profile of Mood States Questionnaire (POMSQ), and Ten-Statement Rosenberg self-esteem scale (TSRSE), HC participants’ liver enzymes, alanine transaminase (ALT), and aspartate transaminase (AST) were assessed.
Results:
Significant improvements of POMSQ, BDI, AST, IIEF-5, ALT, and TSRSE within the WEG only were seen. No significant changes occurred in the control group’s parameters.
Conclusions:
Exercise (walking) is a good modality to improve liver enzymes, ED, and ED-associated psychological burden (depression, low self-esteem, and mood disturbances) in HC men with ED.
Keywords
exercise, liver enzymes, erectile dysfunction, mood disturbance, depression, hepatitis C
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