Short-term effectiveness and safety of CT-guided radioactive iodine-125 seed implantation for treatment of adrenal metastases

Yingwen Hou; Ruibao Liu; Yali Cui; Yan Liu; Houbin Sun; Yi Yang; Linan Yin

doi:10.5114/jcb.2022.115194

Abstract

2/2022 vol. 14

Original paper

Short-term effectiveness and safety of CT-guided radioactive iodine-125 seed implantation for treatment of adrenal metastases

Yingwen Hou ¹

,

Ruibao Liu ¹

,

Yali Cui ¹

,

Yan Liu ¹

,

Houbin Sun ¹

,

Yi Yang ¹

,

Linan Yin ¹

Department of Interventional Radiology, Harbin Medical University Cancer Hospital, Harbin, China

J Contemp Brachytherapy 2022; 14, 2: 148–156

DOI: https://doi.org/10.5114/jcb.2022.115194

Online publish date: 2022/04/01

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AMA

Hou Y, Liu R, Cui Y, et al. Short-term effectiveness and safety of CT-guided radioactive iodine-125 seed implantation for treatment of adrenal metastases. Journal of Contemporary Brachytherapy. 2022;14(2):148-156. doi:10.5114/jcb.2022.115194.

APA

Hou, Y., Liu, R., Cui, Y., Liu, Y., Sun, H., & Yang, Y. et al. (2022). Short-term effectiveness and safety of CT-guided radioactive iodine-125 seed implantation for treatment of adrenal metastases. Journal of Contemporary Brachytherapy, 14(2), 148-156. https://doi.org/10.5114/jcb.2022.115194

Chicago

Hou, Yingwen, Ruibao Liu, Yali Cui, Yan Liu, Houbin Sun, Yi Yang, and Linan Yin. 2022. "Short-term effectiveness and safety of CT-guided radioactive iodine-125 seed implantation for treatment of adrenal metastases". Journal of Contemporary Brachytherapy 14 (2): 148-156. doi:10.5114/jcb.2022.115194.

Harvard

Hou, Y., Liu, R., Cui, Y., Liu, Y., Sun, H., Yang, Y., and Yin, L. (2022). Short-term effectiveness and safety of CT-guided radioactive iodine-125 seed implantation for treatment of adrenal metastases. Journal of Contemporary Brachytherapy, 14(2), pp.148-156. https://doi.org/10.5114/jcb.2022.115194

MLA

Hou, Yingwen et al. "Short-term effectiveness and safety of CT-guided radioactive iodine-125 seed implantation for treatment of adrenal metastases." Journal of Contemporary Brachytherapy, vol. 14, no. 2, 2022, pp. 148-156. doi:10.5114/jcb.2022.115194.

Vancouver

Hou Y, Liu R, Cui Y, Liu Y, Sun H, Yang Y et al. Short-term effectiveness and safety of CT-guided radioactive iodine-125 seed implantation for treatment of adrenal metastases. Journal of Contemporary Brachytherapy. 2022;14(2):148-156. doi:10.5114/jcb.2022.115194.

Purpose

To evaluate short-term effectiveness and safety of computed tomography (CT)-guided radioactive iodine-125 (125I) seed implantation (CTRISI) for treating adrenal metastases.

Material and methods

A total of 50 consecutive patients with adrenal metastases were enrolled retrospectively. Among them, 18 patients received CTRISI, and 18 received 3D-conformal radiotherapy (3D-CRT) treatment. The remaining 14 patients without any treatments served as a control group. Follow-up CT was performed at 6 weeks, 3 months, and 6 months after treatment. Tumor responses and complications were evaluated.

Results

At 6 weeks, control rate in control group (complete response [CR] + partial response [PR]) was 0, and in the CTRISI group (CR + PR, 84.41%), it was significantly higher than that in the 3D-CRT group (CR + PR, 44.44%). Local control rates with CTRISI at 3 and 6 months were 68.42% and 57.89%, respectively. No severe complications were observed after CTRISI.

Conclusions

CTRISI is an effective and safe method for short-term treatment of adrenal metastases. Our findings suggest that CTRISI can safely and effectively be used for adrenal metastases patients as short-term treatment. Further survival studies with longer follow-up are warranted to validate our results.

Keywords

125I seeds, adrenal metastases, brachytherapy, short-term, CT-guided

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