eISSN: 1897-4317
ISSN: 1895-5770
Gastroenterology Review/Przegląd Gastroenterologiczny
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3/2014
vol. 9
 
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abstract:
Review paper

The effect of drugs and stimulants on gastric myoelectrical activity

Krzysztof Jonderko
,
Jarosław Kwiecień
,
Anna Kasicka-Jonderko
,
Magdalena Buschhaus

Prz Gastroenterol 2014; 9 (3): 130–135
DOI: https://doi.org/10.5114/pg.2014.43573
Online publish date: 2014/06/26
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Electrogastrography (EGG) is a non-invasive diagnostic method useful for the registration and analysis of gastric myoelectrical activity. Abnormalities within an electrogastrogram were found to correlate with a number of disorders and symptoms, like functional dyspepsia, diabetic gastroparesis and terminal hepatic or renal failure. The EGG is also a valuable diagnostic method enabling the evaluation of the effect of drugs on gastric myoelectrical activity, which can be intentional, as in the case of prokinetics, or can have an adverse character. Our review focuses on drugs with a proven impact on gastric myoelectrical activity and hence on the electrogastrogram. The paper assembles and discusses the results of investigations dealing with changes in the electrogastrograms evoked by various drugs. Moreover, the mechanisms of the influence on the gastric myoelectrical activity of drugs, curative substances and stimulants are presented.
keywords:

drugs, drug adverse effects, electrogastrography, gastric myoelectrical activity, prokinetics
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