eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
4/2015
vol. 40
 
Share:
Send email
Share:
abstract:
Review paper

Venous thromboembolism and sarcoidosis: co-incidence or coexistence?

Anna Goljan-Geremek
,
Marcin Geremek
,
Elzbieta Puscinska
,
Pawel Sliwinski

(Cent Eur J Immunol 2015; 40 (4): 477-480)
DOI: https://doi.org/10.5114/ceji.2015.56972
Online publish date: 2016/01/15
View full text Get citation
 
PlumX metrics:
The association between venous thromboembolism (VTE) and sarcoidosis has been reported recently, nevertheless the true incidence of co-incident sarcoidosis and VTE is unknown. Sarcoidosis as a chronic disease of immune dysregulation might be associated with an increased risk of VTE. The mechanisms responsible for VTE development are not clear and may be influenced by several factors: activity of inflammation, clinical characteristics of sarcoidosis and comorbidities. Pulmonary embolism (PE) as a potentially fatal condition should be considered in all of the patients with sarcoidosis in whom worsening of the respiratory status is diagnosed. A high plasma D-dimers (DD) level may be suggestive of VTE, nevertheless elevated plasma DD should be interpreted with caution, in the context of the active inflammatory process. If sarcoidosis appears to be one of risk factors for VTE development, further investigations are needed to define the pro-thrombotic phenotype of this disease.
keywords:

sarcoidosis, inflammation, venous thromboembolism

Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.