1. Kowalski ML, Agache I, Bavbek S, et al. Diagnosis and management of NSAID-exacerbated respiratory disease (N-ERD) – a EAACI position paper. Allergy 2019; 74: 28-39.
2.
Rajan JP, Wineinger NE, Stevenson DD, et al. Prevalence of aspirin-exacerbated respiratory disease among asthmatic patients: a meta-analysis of the literature. J Allergy Clin Immunol 2015; 135: 676-81.
3.
Bavbek S, Dursun B, Dursun E, et al. The prevalence of aspirin hypersensitivity in patients with nasal polyposis and contributing factors. Am J Rhinol Allergy 2011; 25: 411-5.
4.
Szczeklik A, Niżankowska E, Duplaga M; AIANE investigatiors. Natural history of aspirin-induced asthma. Eur Respir J 2000; 16: 432-6.
5.
Berges-Gimeno MP, Simon RA, Stevenson DD. The natural history and clinical chracteristics of aspirin-exacerbated respiratory disease. Ann Allergy Asthma Immunol 2002; 89: 474-8.
6.
Mascia K, Haselkorn T, Deniz YM, et al. Aspirin sensitivity and severity of asthma: evidence for irreversible airway obstruction in patients with difficult-to treat asthma. J Allergy Clin Immunol 2005; 116: 970-5.
7.
Stevens WW, Peters AT, Hirsch AG, et al. Clinical characteristics of patients with chronic rhinosinusitis with nasal polyps, asthma, and aspirin-exacerbated respiratory disease. J Allergy Clin Immunol Pract 2017; 5: 1061-70e3.
8.
Mullol J, Boyce J, Dahlen SE, et al. Eicosanoid dysregulation and type 2 inflammation in AERD. J Allergy Clin Immunol 2021; 148: 1157-60.
9.
Sehanobish E, Asad M, Barbi M, et al. Aspirin actions in treatment of NSAID-exacerbated respiratory disease. Front Immunol 2021; 12: 695815.
10.
Steinke JW, Payne SC, Borish L. Eosinophils and mast cells in aspirin-exacerbated respiratory disease. Immunol Allergy Clin North Am 2016; 36: 719-34.
11.
Jakiela B, Soja S, Sladek K, et al. Heterogeneity of lower airway inflammation in patients with NSAID-exacerbated respiratory disease. J Allergy Clin Immunol 2021; 147: 1318-28e5.
12.
Gevaert P, Omachi TA, Corren J, et al. Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials. J Allergy Clin Immunol 2020; 146: 595-605.
13.
Bachert C, Han JK, Desrosiers M, et al. Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials. Lancet 2019; 394: 1638-50.
14.
Laidlaw TM, Buchheit KM, Cahill KM, et al. Efficacy of tezepelumab in patients with severe, uncontrolled asthma and aspirin-exacerbated respiratory disease in NAVIGATOR. J Allergy Clin Immunol Pract 2025; 13: 1855-8e2.
15.
Hayashi H, Mitsui C, Nakatani E, et al. Omalizumab reduces cysteinyl leukotriene and 9α,11β-prostaglandin F2 overproduction in aspirin-exacerbated respiratory disease. J Allergy Clin Immunol 2016; 137: 1585-7.
16.
Hayashi H, Fukutomi Y, Mitsui C, et al. Omalizumab for aspirin hypresensitivity and leukotriene overproduction in aspirin-exacerbated respiratory disease. A randomized controlled trial. Am J Respir Crit Care Med 2020; 201: 1488-98.
17.
Quint T, Dahm V, Arnoldner MA, et al. Omalizumab-induced aspirin tolerance in non-steroidal anti-inflammatory drug-exacerbated respiratory disease patients is independent of atopic sensitization. J Allergy Clin Immunol 2022; 10: 506-16.
18.
Hayashi H, Fukutomi Y, Mitsui C, et al. Omalizumab ameliorated extrarespiratory symptoms in patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol 2023; 151: 1667-72.
19.
Boyce JA. Aspirin sensitivity: lessons in the regulation and dysregulation of mast cell function. J Allergy Clin Immunol 2019; 144: 875-81.
20.
Buchheit KM, Sohail A, Hacker J, et al. Rapid and sustained effect of dupilumab on clinical and mechanistic outcomes in aspirin-exacerbated respiratory disease. J Allergy Clin Immunol 2022; 150: 415-24.
21.
Schneider S, Poglitsch K, Morgenstern C, et al. Dupilumab increases aspirin tolerance in NSAID-exacerbated respiratory disease. Eur Respir J 2023; 61: 2201335.
22.
Steinke JW, Payne SC, Borish L. Interleukin-4 in the generation of the AERD phenotype: implications for molecular mechanisms driving therapeutic benefit of aspirin desensitization. J Allergy (Cairo) 2012: 182090.
23.
Hayashi Y, Kouyashi M, Kuwata H, et al. Interferon gamma and interleukin 4 inhibit interleukin 1-beta induced delayed prostaglandin E2 generation through suppression of cyclooxgenase 2 expression in human fibroblasts. Cytokine 2000; 12: 601-12.
24.
Picado C, Mulloll J, Roca-Ferrer J. Mechanisms by which dupilumab normalizes eicosanoid metabolism and restores aspirin-tolerance in AERD: a hypothesis. J Allergy Clin Immunol 2023; 151: 310-3.
25.
Martin H, Barrett NA, Laidlaw T. Mepolizumab does not prevent all aspirin-induced reactions in patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol Pract 2020; 9: 1384-5.
26.
Sanchez J, Garcia E, Lopez JF, et al. Nonsteroidal anti-inflammatory drug (NSAID) tolerance after biological therapy in patients with NSAID-exacerbated respiratory disease: a randomized comparative trial. J Allergy Clin Immunol Pract 2023; 11: 2172-9.
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