Corticosteroid dependence and corticosteroid resistance in Crohn’s disease

Zbigniew Śliwiński

eISSN: 1897-4317
ISSN: 1895-5770

Gastroenterology Review/Przegląd Gastroenterologiczny

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6/2009
vol. 4

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abstract:

Review paper

Corticosteroid dependence and corticosteroid resistance in Crohn’s disease

Zbigniew Śliwiński

Przegląd Gastroenterologiczny 2009; 4 (6): 288-292

Online publish date: 2009/12/22

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Corticosteroids (CS) have been used over 50 years to treat patients with inflammatory bowel disease. Fraction of patients do not respond to CS, and others responding to treatment come to dependence on this drug. In this paper the mechanisms of CS action were briefly discussed and possible molecular causes of CS-resistance and CS-dependence proposed.

keywords:

Corticosteroid dependence and corticosteroid resistance in Crohn’s disease

Zbigniew Śliwiński

corticosteroids, corticosteroid-resistance, corticosteroid-dependence, Crohn’s disease