eISSN: 1897-4317
ISSN: 1895-5770
Gastroenterology Review/Przegląd Gastroenterologiczny
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SCImago Journal & Country Rank
3/2020
vol. 15
 
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abstract:
Original paper

Incidence of genes encoding vanA/vanB vancomycin resistance in rectal swabs of patients with diagnosed cancer, on the day of admission to hospital, in a non-epidemic period

Maria Szymankiewicz
1
,
Joanna Wróblewska
1
,
Tomasz Nowikiewicz
2, 3

1.
Department of Microbiology, Prof. F. Łukaszczyk Centre of Oncology, Bydgoszcz, Poland
2.
Chair and Clinic of Oncological Surgery, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland
3.
Clinical Department of Breast Cancer and Reconstructive Surgery, Prof. F. Łukaszczyk Centre of Oncology, Bydgoszcz, Poland
Gastroenterology Rev 2020; 15 (3): 220–224
Online publish date: 2020/09/19
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Introduction
Rapid diagnosis is important for preventing infections due to vancomycin-resistant enterococci.

Aim
To evaluate the status of gastrointestinal colonisation with strains containing vanA/vanB genes in oncological patients.

Material and methods
A total of 167 samples of rectal swabs taken from 161 patients (mean age: 63, range: 29–93 years) were examined, including 113 patients from surgical wards (70.2%) and 48 patients from non-surgical wards (29.8%), with diagnosed cancer. The tests were carried out within 24 h of admitting the patient to the department, using the Cepheid Xpert vanA/vanB test, with a CE marked GeneXpert® Instrument Systems analyser. Samples with positive vanB gene results were additionally seeded on chromogenic media.

Results
The presence of the vanA gene was found in 2.7% and 6.3% of the examined patients, respectively, from the surgi- cal and non-surgical departments, which accounted for 3.7% of all the patients examined. The presence of the vanB gene was detected in 21.1% of the patients, but in no case was there any growth of vancomycin-resistant enterococci on the chromogenic medium.

Conclusions
Patients admitted to non-surgical wards were more often colonised with vanA/vanB genes than were patients admitted to surgical wards, but the differences were not statistically significant.

keywords:

colonisation, vanA/vanB enterococci, oncological patients

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