eISSN: 2450-4459
ISSN: 2450-3517
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4/2018
vol. 4
 
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abstract:
Review paper

Treatment challenges in elderly diabetics

Janina Kokoszka-Paszkot

Online publish date: 2018/10/15
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In 2017 the proportion of people aged 65 years and over reached 14% of the total Polish population. Eurostat predicts that Poland will become one of the oldest European populations by 2060. 25–30% of the elderly are estimated to be affected by diabetes mellitus. Studies of elderly diabetics proved the efficacy and safety of DPP-4 inhibitors with minor hypoglycaemia risk, lack of fracture risk and weight gain, as well as neutral or even reduced cardiovascular complications and mortality. The studies’ results show DPP-4 to be an effective and safe alternative therapy for elderly diabetics with chronic kidney disease. Co-morbidities, especially chronic kidney disease, cognitive impairment, and frailty syndrome should be considered during therapy of elderly diabetics. Modern therapies (gliptins) seem to be a very interesting option in the elderly population.
keywords:

diabetes mellitus, elderly, gliptins, chronic kidney disease

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