Underlying causes of cerebral palsy: public health perspectives

Gulnara Kapanova; Shynar Malik; Aima Adylova

doi:10.5114/fn.2021.112019

eISSN: 1509-572x
ISSN: 1641-4640

Folia Neuropathologica

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4/2021
vol. 59

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abstract:

Review paper

Underlying causes of cerebral palsy: public health perspectives

Gulnara Kapanova

¹

,

Shynar Malik

¹

,

Aima Adylova

²

Al Farabi Kazakh National University, Kazakhstan

Kazakhstan School of Public Health, Kazakhstan

Folia Neuropathol 2021; 59 (4): 386-392

DOI: https://doi.org/10.5114/fn.2021.112019

Online publish date: 2021/12/30

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Cerebral palsy (CP) is a neurological pathology that is characterized by a combination of signs and symptoms that occur in neurodegenerative or metabolic disorder during the first few years of life. It is a complex pathology orchestrated by a plethora of different causes. The current diagnostic regimen for CP involves brain magnetic resonance imaging (MRI), and antenatal and perinatal insult. Despite advances in the field of genetics and molecular biology, the evaluating the underlying causes of this severe pathology are still bleak. In this review we have attempted to provide a landscape of the underlying mechanisms of cerebral palsy. We have partitioned this review broadly into genetic and proteomic-based studies, which have enriched our understanding about the pathogenesis of CP.

keywords:

Underlying causes of cerebral palsy: public health perspectives

Gulnara Kapanova 1 , Shynar Malik 1 , Aima Adylova 2

cerebral palsy, neuropathology, disease

Gulnara Kapanova

¹

,

Shynar Malik

¹

,

Aima Adylova

²