eISSN: 1509-572x
ISSN: 1641-4640
Folia Neuropathologica
Current issue Archive Manuscripts accepted About the journal Abstracting and indexing Subscription Contact Instructions for authors
SCImago Journal & Country Rank
1/2018
vol. 56
 
Share:
Share:
more
 
 
abstract:
Review paper

Visualization of synaptic vesicle dynamics with fluorescence proteins

Wang Li, Chunyang Geng, Bo Liu

Folia Neuropathol 2018; 56 (1): 21-29
Online publish date: 2018/03/28
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Synaptic vesicle (SV) will be transported to the bouton along the axon, once it is formed in a cell body. After docking in the active zone, neurotransmitters will be released upon the stimulation, and then transmission of chemical signals will be initiated. Presently, many advanced technologies and burgeoning molecular sensors are being used to explore the synaptic transmission. These studies provide a new sight into the presynaptic structure and its function. The present review summarizes the application of fluorescent proteins (FPs) for SV tracking and recycling. Some FPs and relevant imaging technologies such as fluorescence resonance energy transfer (FRET), fluorescence recovery after photobleaching (FRAP) and fluorescence lifetime imaging microscopy (FLIM), are introduced here. In addition, some examples are also analyzed to visualize the dynamics of SVs in living cells with the help of some FPs.
keywords:

synaptic vesicle, fluorescent proteins, fluorescent technologies, dynamics

Quick links
© 2018 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe