Allergic response to nasal administration of dexpanthenol
in a child. A case report and a review of the literature

Mikołaj Turski; Małgorzata Łukasiewicz; Piotr Sajdak; Seweryn Ziajor; Artur Bednarski; Justyna Tomasik; Marcel Stodolak

doi:10.5114/pja.2024.135507

eISSN: 2391-6052
ISSN: 2353-3854

Alergologia Polska - Polish Journal of Allergology

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Allergic response to nasal administration of dexpanthenol in a child. A case report and a review of the literature

Mikołaj Turski

¹

,

Małgorzata Łukasiewicz

²

,

Piotr Sajdak

³

,

Seweryn Ziajor

³

,

Artur Bednarski

⁴

,

Justyna Tomasik

⁵

,

Marcel Stodolak

¹

Department of Pediatrics, E.Szczeklik Specialist Hospital, Tarnów, Poland

CenterMed Medical Centre, Tarnów, Poland

Medical Centre of Łańcut, Poland

Morphological Sciences Department, Institute of Medical Sciences, Medical Collage of University, Rzeszów, Poland

Medical University, Lublin, Poland

Alergologia Polska – Polish Journal of Allergology 2024; 11, 1: 76–79

DOI: https://doi.org/10.5114/pja.2024.135507

Data publikacji online: 2024/02/17

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AMA

Turski M, Łukasiewicz M, Sajdak P, et al. Allergic response to nasal administration of dexpanthenol
in a child. A case report and a review of the literature. Alergologia Polska - Polish Journal of Allergology. 2024;11(1):76-79. doi:10.5114/pja.2024.135507.

APA

Turski, M., Łukasiewicz, M., Sajdak, P., Ziajor, S., Bednarski, A.,  & Tomasik, J. et al. (2024). Allergic response to nasal administration of dexpanthenol
in a child. A case report and a review of the literature. Alergologia Polska - Polish Journal of Allergology, 11(1), 76-79. https://doi.org/10.5114/pja.2024.135507

Chicago

Turski, Mikołaj, Małgorzata Łukasiewicz, Piotr Sajdak, Seweryn Ziajor, Artur Bednarski, Justyna Tomasik,  and Marcel Stodolak. 2024. "Allergic response to nasal administration of dexpanthenol
in a child. A case report and a review of the literature". Alergologia Polska - Polish Journal of Allergology 11 (1): 76-79. doi:10.5114/pja.2024.135507.

Harvard

Turski, M., Łukasiewicz, M., Sajdak, P., Ziajor, S., Bednarski, A., Tomasik, J.,  and Stodolak, M. (2024). Allergic response to nasal administration of dexpanthenol
in a child. A case report and a review of the literature. Alergologia Polska - Polish Journal of Allergology, 11(1), pp.76-79. https://doi.org/10.5114/pja.2024.135507

MLA

Turski, Mikołaj et al. "Allergic response to nasal administration of dexpanthenol
in a child. A case report and a review of the literature." Alergologia Polska - Polish Journal of Allergology, vol. 11, no. 1, 2024, pp. 76-79. doi:10.5114/pja.2024.135507.

Vancouver

Turski M, Łukasiewicz M, Sajdak P, Ziajor S, Bednarski A, Tomasik J et al. Allergic response to nasal administration of dexpanthenol
in a child. A case report and a review of the literature. Alergologia Polska - Polish Journal of Allergology. 2024;11(1):76-79. doi:10.5114/pja.2024.135507.

Metryki PlumX:

A 2-year-old boy with suspected lactose intolerance developed an extensive, itchy rash after using a nasal spray containing dexpanthenol. He was initially treated for a viral upper airway infection with ibuprofen, xylometazoline, and cetirizine. A switch to a drug containing dexpanthenol led to the appearance of the rash and subsequent sleep deprivation. No other possible cause of allergy was found. The withdrawal of all drugs but cetirizine led to full recovery. Dexpanthenol, an alcohol analog of vitamin B5, is present in many drugs for its positive impact on tissue repair. Although generally considered safe, it may rarely cause an allergic reaction, hence we underscore the importance of considering dexpanthenol oversensitivity in patients with unexplained widespread rashes, particularly in pediatric cases.

Allergic response to nasal administration of dexpanthenol in a child. A case report and a review of the literature

Mikołaj Turski 1 , Małgorzata Łukasiewicz 2 , Piotr Sajdak 3 , Seweryn Ziajor 3 , Artur Bednarski 4 , Justyna Tomasik 5 , Marcel Stodolak 1

Mikołaj Turski

¹

,

Małgorzata Łukasiewicz

²

,

Piotr Sajdak

³

,

Seweryn Ziajor

³

,

Artur Bednarski

⁴

,

Justyna Tomasik

⁵

,

Marcel Stodolak

¹