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Gastroenterology Review/Przegląd Gastroenterologiczny
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vol. 12
 
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The efficacy and duration of treatment with propranolol in children with cyclic vomiting syndrome in southern Iran

Mahmoud Haghighat, Hajar Memari, Naser Honar, Seyed Mohsen Dehghani, Mohammad-Hadi Imanieh, Seyed-Javad Injoo, Hazhir Javaherizadeh

Data publikacji online: 2017/12/14
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Introduction: Cyclic vomiting syndrome is a functional disorder characterised by repeated episodes of nausea and vomiting with symptom-free intervals between the attacks. Cyclic vomiting syndrome is a migraine equivalent; therefore, anti-migraine medications are effective for cyclic vomiting syndrome prophylaxis, but duration of treatment is not clear.

Aim: To determine the efficacy and duration of drug therapy in cyclic vomiting syndrome.

Material and methods: This study was conducted on 206 cases of cyclic vomiting syndrome, who were treated with propranolol as prophylaxis. After they were symptom-free for at least 9 months, propranolol was tapered and discontinued and then they were followed for at least 6 months after drug withdrawal for evaluation of recurrence.

Results: The study subjects included 127 boys and 79 girls. The mean age of symptom onset was 3.4 years (range: 3 months to 14.5 years) and the mean age at the time of diagnosis was 5.7 years (range: 8.4 months to 18 years). Among the 206 patients in whom propranolol was discontinued, only 16 (7.8%) subjects developed recurrence of symptoms in the 6-month follow-up period.

Conclusions: There is no need to continue prophylaxis of cyclic vomiting syndrome for a long time. It is also possible to make the duration of drug therapy shorter, which is useful for the convenience of the patients and prevention of drug side effects.
referencje:
Lee LY, Abbott L, Moodie S, et al. Cyclic vomiting syndrome in 28 patients: demographics, features and outcomes. Eur J Gastroenterol Hepatol 2012; 24: 939-43.
Sunku B. Cyclic vomiting syndrome: a disorder of all ages. Gastroenterol Hepatol 2009; 5: 507-15.
Lin YP, Ni YH, Weng WC, et al. Cyclic vomiting syndrome and migraine in children. J Formos Med Assoc 2011; 110: 382-7.
Hejazi RA, McCallum RW. Cyclic vomiting syndrome in adults: rediscovering and redefining an old entity. Aliment Pharmacol Ther 2011; 34: 263-73.
Shin YK, Kwon JG, Kim KY, et al. A case of cyclic vomiting syndrome responding to gonadotropin-releasing hormone analogue. J Neurogastroenterol Motil 2010; 16: 77-82.
Pareek N, Fleisher DR, Abell T. Cyclic vomiting syndrome: what a gastroenterologist needs to know. Am J Gastroenterol 2007; 102: 2832-40.
Erturk O, Uluduz D, Karaali-Savrun F. Efficacy of nebivolol and amitriptyline in the prophylaxis of cyclic vomiting syndrome: a case report. Neurologist 2010; 16: 313-4.
Hejazi RA, Reddymasu SC, Namin F, et al. Efficacy of tricyclic antidepressant therapy in adults with cyclic vomiting syndrome: a two-year follow-up study. J Clin Gastroenterol 2010; 44: 18-21.
Forbes D, Fairbrother S. Cyclic nausea and vomiting in childhood. Aust Fam Physician 2008; 37: 33-6.
Olmez A, Kose G, Turanli G. Cyclic vomiting with generalized epileptiform discharges responsive to topiramate therapy. Pediatr Neurol 2006; 35: 348-51.
Yang HR. Recent concepts on cyclic vomiting syndrome in children. J Neurogastroenterol Motil 2010; 16: 139-47.
Li BU, Lefevre F, Chelimsky GG, et al. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition consensus statement on the diagnosis and management of cyclic vomiting syndrome. J Pediatr Gastroenterol Nutr 2008; 47: 379-93.
Chow S, Goldman RD. Treating children’s cyclic vomiting. Can Fam Physician 2007; 53: 417-9.
Sudel B, Li BU. Treatment options for cyclic vomiting syndrome. Curr Treat Options Gastroenterol 2005; 8: 387-95.
Paul SP, Barnard P, Soondrum K, et al. Antimigraine (low-amine) diet may be helpful in children with cyclic vomiting syndrome. J Pediatr Gastroenterol Nutr 2012; 54: 698-9.
Abraham MB, Porter P. Clonidine in cyclic vomiting. J Pediatr Gastroenterol Nutr 2011; 53: 219-21.
Haan J, Kors EE, Ferrari MD. Familial cyclic vomiting syndrome. Cephalalgia 2002; 22: 552-54.
Hikita T, Kodama H, Kaneko S, et al. Sumatriptan as a treatment for cyclic vomiting syndrome: a clinical trial. Cephalalgia 2011; 31: 504-7.
Lee LY, Abbott L, Mahlangu B, et al. The management of cyclic vomiting syndrome: a systematic review. Eur J Gastroenterol Hepatol 2012; 24: 1001-6.
Li BU, Misiewicz L. Cyclic vomiting syndrome: a brain-gut disorder. Gastroenterol Clin North Am 2003; 32: 997-1019.
Li BU, Balint JP. Cyclic vomiting syndrome: evolution in our understanding of a brain-gut disorder. Adv Pediatr 2000; 47: 117-60.
Haghighat M, Rafie SM, Dehghani SM, et al. Cyclic vomiting syndrome in children: experience with 181 cases from southern Iran. World J Gastroenterol 2007; 13: 1833-6.
Boles RG, Lovett-Barr MR, Preston A, et al. Treatment of cyclic vomiting syndrome with co-enzyme Q10 and amitriptyline, a retrospective study. BMC Neurol 2010; 10: 10.
Hejazi RA, Lavenbarg TH, Foran P, et al. Who are the nonresponders to standard treatment with tricyclic antidepressant agents for cyclic vomiting syndrome in adults? Aliment Pharmacol Ther 2010; 31: 295-301.
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