On behalf of KROK investigators:

Witold Gerber – Polish-American Heart Clinics, Bielsko-Biala, Poland

Remigiusz Tomczyk – 10th Military Clinical Hospital with Polyclinic SPZOZ, Bydgoszcz, Poland

Wojciech Pawliszak – University Hospital, Bydgoszcz, Poland

Progressive degeneration of dopamine neurons in the substantia nigra is the primary pathological abnormality in Parkinson’s disease (PD). It has been demonstrated that overactivation of glutamatergic neurons leads to excessive accumulation of intracellular calcium and impairs autophagy. To assess...