Guidelines for Clostridium difficile infection in adults

Michał Kukla; Krystian Adrych; Agnieszka Dobrowolska; Tomasz Mach; Jarosław Reguła; Grażyna Rydzewska

doi:10.5114/pg.2020.93629

eISSN: 1897-4317
ISSN: 1895-5770

Gastroenterology Review/Przegląd Gastroenterologiczny

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1/2020
vol. 15

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abstract:

Special paper

Guidelines for Clostridium difficile infection in adults

Michał Kukla

^{1, 2}

,

Krystian Adrych

³

,

Agnieszka Dobrowolska

⁴

,

Tomasz Mach

⁵

,

Jarosław Reguła

^{6, 7}

,

Grażyna Rydzewska

^{8, 9}

Department of Internal Medicine and Geriatrics, Jagiellonian University Medical College, Krakow, Poland

Department of Endoscopy, University Hospital, Krakow, Poland

Department of Gastroenterology and Hepatology, Medical University of Gdansk, Gdansk, Poland

Department of Gastroenterology, Dietetics and Internal Diseases, Poznan University of Medical Sciences, Poznan, Poland

Department of Gastroenterology, Hepatology and Infectious Diseases, Jagiellonian University Medical College, Krakow, Poland

Department of Gastroenterology, Hepatology and Clinical Oncology, Medical Postgraduate Education Centre, Warsaw, Poland

Department of Gastrointestinal Oncology, "Maria Sklodowska-Curie" Clinical Oncology Institute, Warsaw, Poland

Central Clinical Hospital of Ministry of Inferior and Administration, Warsaw, Poland

Collegium Medicum, Jan Kochanowski University, Kielce, Poland

Gastroenterology Rev 2020; 15 (1): 1–21

DOI: https://doi.org/10.5114/pg.2020.93629

Online publish date: 2020/03/19

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Clostridium difficile infection (CDI) has become a serious medical and epidemiological problem, especially in well developed countries. There has been evident increase in incidence and severity of CDI. Prevention, proper diagnosis and effective treatment are necessary to reduce the risk for the patients, deplete the spreading of infection and diminish the probability of recurrent infection. Antibiotics are the fundamental treatment of CDI. In patients who had recurrent CDI fecal microbiota transplantation seems to be promising and efficient strategy. These guidelines systematize existing data and include recent changes implemented in the management of CDI.

keywords:

Guidelines for Clostridium difficile infection in adults

Michał Kukla 1, 2 , Krystian Adrych 3 , Agnieszka Dobrowolska 4 , Tomasz Mach 5 , Jarosław Reguła 6, 7 , Grażyna Rydzewska 8, 9

Clostridium difficile infection, pseudomembranous colitis, diarrhea, antibacterial treatment, fecal microbiota transplantation

Michał Kukla

^{1, 2}

,

Krystian Adrych

³

,

Agnieszka Dobrowolska

⁴

,

Tomasz Mach

⁵

,

Jarosław Reguła

^{6, 7}

,

Grażyna Rydzewska

^{8, 9}