eISSN: 1897-4317
ISSN: 1895-5770
Gastroenterology Review/Przegląd Gastroenterologiczny
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Review paper

Are Down’s syndrome patients a risk group for celiac disease?

Aleksandra Nowak-Oczkowska, Anna Szaflarska-Popławska, Anetta Soroczyńska-Wrzyszcz

Prz Gastroenterol 2013, 8 (2): 77–85
Celiac disease is a genetically determined enteropathy caused by permanent gluten intolerance. The factors considered as responsible for celiac disease are genetic and environmental factors, as well as auto-immunological processes which lead to chronic inflammation. There are reports in the literature that indicate co-occurrence of celiac disease with many diseases, and one of the reported risk groups of celiac disease is patients with the most frequent chromosome abnormality – Down's syndrome. Many societies and authors recommend screening of this group.

celiac disease, Down's syndrome, incidence, screening

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