eISSN: 2083-8441
ISSN: 2081-237X
Pediatric Endocrinology Diabetes and Metabolism
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SCImago Journal & Country Rank

 
4/2019
vol. 25
 
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Artykuł oryginalny

Korelacja markerów przemiany węglowodanów ze stężeniem witaminy D u nastolatków z nadwagą i otyłością

Anna-Mariia Shulhai
1
,
Halyna Pavlyshyn
1
,
Oleksandra Shulhai
2

1.
Department of Pediatrics No2, I. Horbachevsky Ternopil National Medical University, Ukraine
2.
Department of Children’s Diseases with Pediatric Surgery, I. Horbachevsky Ternopil National Medical University, Ukraine
Pediatr Endocrinol Diabetes Metab 2019; 25 (4): 169-176
Data publikacji online: 2019/11/16
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Introduction
In the case of obesity and excessive body weight, the deficiency of vitamin D increases, which significantly impairs metabolic processes in the body, especially fatty and carbohydrate metabolism. Vitamin D metabolites affect insulin sensitivity of cells.

The aim of the study
was to determine the relationship between vitamin D and carbohydrate metabolism in adolescents with excessive body weight and obesi-ty.

Material and methods
139 adolescents were examined. The mean age of children was 15.5 ±2.3 years. 65 adolescents with excessive weight and 74 obesity teenagers were examined. Parameters that were determined in all children included: undertaking anthropometric measurements, general examinations, biochemical parameters, including carbohydrate metabolism: fasting glucose, insulin, oral glucose tolerant test, measuring the homeostasis model assessment for insulin resistance, blood pressure measurement and determination of vitamin D status.

Results
The features of changes carbohydrate metabolism markers in adolescents with overweight and obesity, depending on the level of serum 25(OH)D, have been established. Correlations between vitamin D status and markers of carbohydrate metabolism such as basal insulin level (p = 0.000) and HOMA-IR index (p = 0.000) and anthropometric indices: body mass index (p = 0.000), waist circumference (p = 0.000) and hip circumference (p = 0.001), waist-hip ratio (p = 0.000), waist-to-height ratio (p = 0.000) have been determined.

Conclusions
The study has established prognostically significant biochemical (basal insulin), and anthropometric (body mass index, waist circumfer-ence, waist-hip ratio, and waist-to-height ratio) markers resulting in vitamin D deficiency development in children with excessive body weight and obesity.

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